|Description||Levomilnacipran (brand name Fetzima) is an antidepressant approved for the treatment of major depressive disorder in the United States. It was developed by Forest Laboratories and Pierre Fabre Group, and was approved by the Food and Drug Administration in July 2013. Levomilnacipran is the levo- enantiomer of milnacipran, and has similar effects and pharmacology, acting as a serotonin-norepinephrine reuptake inhibitor (SNRI).|
Venlafaxine is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class, but it has been referred to as a serotonin-norepinephrine-dopa...
Milnacipran inhibits both norepinephrine transporter (NET) and norepinephrine transporter (SERT) with IC50 of 77 nM and 420 nM, respectively. Milnacipran at hig...
Highly potent H1 histamine receptor antagonist (Kd = 310 pM) and tricyclic antidepressant. Also binds to the H4 histamine receptor (pKi = 6.79).
Fluvoxamine is an antidepressant which functions pharmacologically as a selective serotonin reuptake inhibitor. It is effective in inhibiting 5-ht uptake by blo...
Venlafaxine hydrochloride is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class, but it has been referred to as a serotonin-norep...
Duloxetine Hydrochloride is a serotonin-norepinephrine reuptake inhibitor with Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anx...
Escitalopram, the S-enantiomer of citalopram, belongs to a class of antidepressant agents known as selective serotonin-reuptake inhibitors (SSRIs). Escitalopram...
Fluvoxamine maleate is a selective serotonin (5-HT) reuptake inhibitor (SSRI) and sigma-1 receptor agonist.
Sibutramine hydrochloride monohydrate
A serotonin and noradrenaline reuptake inhibitor (SNR). Decreases calorie intake and increases energy expenditure.
Levomilnacipran (brand name Fetzima) is an antidepressant approved for the treatment of major depressive disorder in the United States. It was developed by Fore...
Trazodone, a phenylpiperazine compound, acts as a serotonin uptake inhibitor with antianxiety (anxiolytic) and sleep-inducing (hypnotic) effects.
Sertraline HCl is a 5-HT antagonist with Ki of 13 nM.
Fluoxetine is a selective serotonin-reuptake inhibitor (SSRI) at the neuronal membrane, used in the treatment of depression.
Paroxetine hydrochloride hemihydrate
Paroxetine hydrochloride hemihydrate is a antidepressant agents known as selective serotonin-reuptake inhibitors (SSRIs).
An antidepressant having effects on the autonomic nervous system; the drug is especially effective for mild and moderate depressions and a combination of Azaphe...
Dapoxetine HCl is a short-acting novel selective serotonin reuptake inhibitor.
Azaphen dihydrochloride monohydrate
Azaphen dihydrochloride monohydrate is a potent inhibitor of the reuptake of serotonin. It is a tricyclic antidepressant (TCA) approved in Russia for the treatm...
class. It delays the reuptake of serotonin, resulting in serotonin persisting longer when it is released. It may also produce some of its effects via its weak 5...
Escitalopram Oxalate also known by the brand names Lexapro and Cipralex among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) ...
Desvenlafaxine Succinate is a new serotonin (5-HT) transporter and norepinephrine (NE) transporter reuptake inhibitor with Ki of 40.2 nM and 558.4 nM respective...