|Description||Levodropropizine possess anti-allergic and inhibits histamine receptor, reduces cough by interfering with stimulus activation of peripheral endings of sensory nerves and by modulation of neuropeptides involved in the cough reflex.|
Loratadine is a histamine H1 receptor antagonist, used to treat allergies. It also acts as a selective inhibitor of B(0)AT2 with IC50 of 4 μM.
FRG-8701 is a novel Histamine H2 receptor antagonist (IC50= 0.25~ 0.43 μM). FRG-8701 has relatively long-lasting antisecretory ef fects in comparison with famot...
Famotine hydrochloride is a histamine H2 receptor antagonist. lt has no effect on the cytochrome P450 enzyme system, and does not appear to interact with other ...
SUVN-G3031 is a Histamine H3 receptor antagonist originated by Suven Life Sciences. Blockade of Histamine H3 receptor can augment the pre-synaptic release of bo...
LY-150310 is a histamine H1-receptor antagonist. It could alter prostanoid concentrations in vitro and in vivo.
Cetirizine, a second-generation antihistamine, is a major metabolite of hydroxyzine. It is a racemic selective H1 receptor inverse agonist. It is used in cutane...
Ranitidine is a histamine H2-receptor antagonist that inhibits stomach acid production. It is commonly used in treatment of peptic ulcer disease and gastroesoph...
This active molecular is a histamine H3 receptor antagonist. The IC50 of Enerisant is 4.9 nM in H3 receptor binding assay using (R)-α-methyl[3H]histamine. In th...
Mizolastine is a histamine H1-receptor antagonist with IC50 of 47 nM used in the treatment of hay fever (seasonal allergic rhinitis), hives and other allergic r...
Pemirolast potassium (BMY 26517) is a histamine H1 antagonist and mast cell stabilizer that acts as an antiallergic agent.
Azatadine is a new antihistamine acts as histamine for histamine H1- receptor inhibitor ( IC50 = 6.5 nM and 10 nM, respectively).
Bavisant dihydrochloride is the dihydrochloride form of Bavisant, which is a highly selective, orally active antagonist of the human H3 receptor. It may be used...
Dexchlorpheniramine maleate, also known as Polaramine, is an antihistamine to treat allergic conditions, urticaria and allergic conjunctivitis and pruritus.
Azelastine HCl is a potent, second-generation, selective, histamine antagonist. It inhibits histamine via competing with histamine for the H1 receptor.
Alcaftadine(R89674) is a H1 histamine receptor antagonist, which is used to prevent eye irritation brought on by allergic conjunctivitis.
Doxylamine succinate competitively inhibits histamine at H1 receptors with substantial sedative and anticholinergic effects.
Ebrotidine(FI 3542), a competitive H2-receptor antagonist, has gastroprotective activity under the condition of gastric mucosal damage caused by some stress res...
Famotidine is a histamine H2-receptor antagonist that inhibits stomach acid production. It is commonly used in the treatment of peptic ulcer disease and gastroe...
Lafutidine, a newly developed histamine H(2)-receptor antagonist, inhibits gastric acid secretion.
Diphenylpyraline, a piperidine derivative, has been found to be a H1 receptor antagonist that could be probably effective against some allergy acts.