|Description||Levodropropizine possess anti-allergic and inhibits histamine receptor, reduces cough by interfering with stimulus activation of peripheral endings of sensory nerves and by modulation of neuropeptides involved in the cough reflex.|
Ketotifen is a second-generation noncompetitive H1-antihistamine and mast cell stabilizer. It is most commonly sold as a salt with fumaric acid, ketotifen fumar...
Acrivastine, also known as BW825C, is an antihistamine with peripheral H1-antagonist potency equal to that of triprolidine for the treatment of allergic rhiniti...
Clemizole is an H1 antagonist acts as a TRPC5 channel blocker (IC50 values are 1.1, 6.4, 9.1, 11.3 and 26.5 μM for TRPC5, TRPC4, TRPC3, TRPC6 and TRPC7 respecti...
Fenspiride is an α adrenergic and H1 histamine receptor antagonist. It is an oxazolidinone spiro compound. It is used as a drug in the treatment of certain resp...
Promethazine hydrochloride is first-generation antihistamine of the phenothiazine family used as an antiallergic, in pruritus, for motion sickness and sedation,...
Mianserin Hydrochloride is a psychoactive drug of the tetracyclic antidepressant.It is classified as a noradrenergic and specific serotonergic antidepressant (N...
Famotidine is a histamine H2-receptor antagonist that inhibits stomach acid production. It is commonly used in the treatment of peptic ulcer disease and gastroe...
Alcaftadine(R89674) is a H1 histamine receptor antagonist, which is used to prevent eye irritation brought on by allergic conjunctivitis.
Betahistine is a H1 receptor agonist, which serves as a vasodilator. It is used in Meniere disease and in vascular headaches but may exacerbate bronchial asthma...
Aceprometazine is a Histamine H1 receptor antagonist as an approved drug. It can be used in combination with meprobamate for the treatment of sleep disorders su...
Meclizine is a histamine H1 receptor antagonist used to treat nausea and motion sickness, has anti-histamine, anti-muscarinic and anti-oxidative phosphorylation...
Alimemazine is a phenothiazine derivative as a Histamine Receptor antagonist. It can be used as an antipruritic . It also acts as a sedative, hypnotic, and anti...
KP136, an antiallergic agent, remarkably inhibited the passive cutaneous anaphylaxis (PCA) with intravenous and oral dosing. KP-136 is an oral potent inhibitor ...
Lafutidine, a newly developed histamine H(2)-receptor antagonist, inhibits gastric acid secretion.
GSK-239512 is a histamine H3 receptor antagonist. In Jun 2015, Phase-II for Schizophrenia in USA was discontinued. Phase II clinical trilas for the treatment of...
Ranitidine is a histamine H2-receptor antagonist that inhibits stomach acid production. It is commonly used in treatment of peptic ulcer disease and gastroesoph...
Fexofenadine inhibits histamine H1 receptor with IC50 of 246 nM.
Loratadine is a histamine H1 receptor antagonist, used to treat allergies. It also acts as a selective inhibitor of B(0)AT2 with IC50 of 4 μM.
Bilastine is a novel, nonsedating H1-antihistamine developed for symptomatic treatment of allergic rhinitis and chronic idiopathic urticaria.
Cetirizine, a second-generation antihistamine, is a major metabolite of hydroxyzine. It is a racemic selective H1 receptor inverse agonist. It is used in cutane...