|Description||Levodropropizine possess anti-allergic and inhibits histamine receptor, reduces cough by interfering with stimulus activation of peripheral endings of sensory nerves and by modulation of neuropeptides involved in the cough reflex.|
Levocabastine is a selective second-generation Histamine H1 receptor antagonist. It is used for Allergic conjunctivitis and Seasonal allergic rhinitis。Levocabas...
(S)-(+)-α-Methylhistamine dihydrobromide is the less active enantiomer of histamine H3 receptor agonist R-(-)-α-methylhistamine, with 120-fold less potent than ...
LY-150310 is a histamine H1-receptor antagonist. It could alter prostanoid concentrations in vitro and in vivo.
Cimetidine, a histamine congener, competitively inhibits histamine binding to histamine H2 receptors.
VUF 5681 dihydrobromide
VUF 5681 dihydrobromide is a potent histamine H3 receptor silent antagonist (pKi = 8.35).
Fenspiride is an α adrenergic and H1 histamine receptor antagonist. It is an oxazolidinone spiro compound. It is used as a drug in the treatment of certain resp...
Tripelennamine hydrochloride, the hydrochloride salt form of tripelennamine, is a blood-brain barrier penetrant and orally active H1-receptor antagonist. Tripel...
Loratadine is a histamine H1 receptor antagonist, used to treat allergies. It also acts as a selective inhibitor of B(0)AT2 with IC50 of 4 μM.
Chlorcyclizine hydrochloride (1:x)
The hydrochloride salt form of Chlorcyclizine which could be used as an antihistamine agent and is also found to have anticholinergic effect at some extent.
GS-283, an isoquinolin derivative, has been found to be histamine receptor and muscarinic receptor blocker.
Bepotastine stimulates P-gp-mediated ATP hydrolysis with Km, Vmax, and Vmax/Km values of 1.25 mM, 108 nmol/min/mg protein, and 0.087 mL/min/mg protein, respecti...
KP136, an antiallergic agent, remarkably inhibited the passive cutaneous anaphylaxis (PCA) with intravenous and oral dosing. KP-136 is an oral potent inhibitor ...
Mebhydroline Napadisylate is an antihistamine used for symptomatic relief of allergic symptoms caused by histamine release, including nasal allergies and allerg...
Dimetotiazine is a histamine H1 receptor antagonist. It is a phenothiazine drug used for the treatment of migraine.
This active molecular is a histamine H3 receptor antagonist. The IC50 of Enerisant is 4.9 nM in H3 receptor binding assay using (R)-α-methyl[3H]histamine. In th...
Diphenhydramine HCl (Benadryl), a histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a ...
JNJ10181457 dihydrochloride is a selective non-imidazole brain penetrant histamine H3 receptor antagonist with pKi values of 8.15 and 8.93 for rat and human H3 ...
JNJ 5207852 dihydrochloride
The hydrochloride salt form of JNJ 5207852, which has been found to be a histamine H3 receptor antagonist and could probably be used against obesity.
Alimemazine is a phenothiazine derivative as a Histamine Receptor antagonist. It can be used as an antipruritic . It also acts as a sedative, hypnotic, and anti...
Ranitidine is a histamine H2-receptor antagonist that inhibits stomach acid production. It is commonly used in treatment of peptic ulcer disease and gastroesoph...