|Description||Leupeptin Hemisulfate is a reversible inhibitor of serine and cysteine proteases.|
NO-5334 is cathepsin K inhibitor Ki values of 0.1 nM for human. It can improve bone strength by preferentially increasing cortical bone mass in ovariectomized r...
Cathepsin S inhibitor
Cathepsin S is expressed in antigen-presenting cells and plays a role in invariant chain processing and major histocompatibility complex class II (MHCII) antige...
JNJ10311795 is a dual inhibitor of Chymase and leukocyte Proteases Cathepsin G. It has inflammation therapeutic efficacy in animals models.
Pepstatin A is a potent aspartic protease inhibitor, and also inhibits HIV replication.It is a hexa-peptide containing the unusual amino acid statine (Sta, (3S,...
CA-074 methyl ester
CA-074 Me is a membrane-permeable inhibitor of irreversible cathepsin B derived from CA-074. CA-074 Me would be hydrolyzed by intracellular esterases to CA-074,...
Leupeptin Hemisulfate is a reversible inhibitor of serine and cysteine proteases.
The cathepsin K inhibitor AAE-581 (balicatib) as the most advanced of them passed Phase II clinical trials in 2005. Eighty adult female Macaca fascicularis unde...
VBY-825 is a potent inhibitor of the assayed cathepsins and its potency against at least one cathepsin, cathepsin S, extends across species relevant for pharmac...
E-64 is an irreversible and selective cysteine protease inhibitor with IC50 of 9 nM for papain.
Odanacatib, also known as MK-0822, is an inhibitor of cathepsin K with potential anti-osteoporotic activity. Odanacatib selectively binds to and inhibits the ac...