|Description||LDN-27219 is a revesible inhibitor of transglutaminase 2 (TG2) that binds to the GTP binidng site of the enzyme and inhbits activity with and IC50 of 600 nM.|
|Synonyms||LDN 27219; LDN 27219|
Ginsenoside Rf, extracted from the traditional Chinese herb ginseng, an anti-arthritic agent, attenuating collagen-induced arthritis in mice.
This molecular is developed as a novel bradycardiac agent through organic synthesis.
Chlophenadione, an analogue of bromindione, could be used as an orally bioavaliable anticoagulant.
Oroxylin A possessed abilities of inhibiting the ATRA-induced IL-6 production via modulation of LAP/LIP/CHOP in leukemia cell lines, which could providing a the...
K-7174, one of proteasome inhibitory homopiperazine derivatives, exhibits a therapeutic effect, which is stronger when administered orally than intravenously, w...
Propylhexedrine Hydrochloride is an α-adrenergic sympathomimetic amine. It acts as a local vasoconstrictor. It is a stimulant drug that is used medicinally as a...
Mulberroside A, extracted from the root bark of white mulberry, could reduce P-gp expression and function being along with the activation of PKC and NF-κB. It h...
Benzoylhypacoitine is extracted from the roots of Aconitum carmichaeli Debx. It might be the principal active components which affect mitochondrial growth by Fu...
Deoxynojirimycin inhibits mammalian glucosidase 1. As well, it inhibits intestinal and lysosmal alpha-glucosidases, beta-glucosidase from sweet almonds, pancrea...
BPH-652, also known as BMS-187745, has been found to be a SQS inhibitor that could probably be effective against S. aureus infections.
Ro 48-8071 fumarate
Ro 48-8071 is an orally active cholesterol synthesis inhibitor or a 2,3-oxidosqualene:lanosterol cyclase (OSC) inhibitor. OSC (EC 188.8.131.52) represents a unique ...
This active molecular, also known as GSK-557296B is a selective, sub-nanomolar (Ki=0.13 nM) oxytocin receptor antagonist with more than 30000-fold selectivity o...
This active molecular is a synthetic glucocorticoid with immunosuppressive and anti-inflammatory properties. Hydrocortamate hydrochloride is applicated for the ...
Dronedarone is a Class III antiarrhythmic and a multi-channel blocker for atrial fibrillation. It blocks potassium, sodium, and calcium channels and also exhibi...
CVT-3369, a piperazineacetic acid derivative, is probably effective in some of biological studies.
Dexrazoxane hydrochloride is an intracellular iron chelator, which decreases the formation of superoxide radicals, used as a cardioprotective agent.
This active molecular is a selective and potent NK(3) antagonist. It has a high affinity for recombinant human (pK(i) value 8.9) and native guinea pig (pK(i) va...
D-Glucosamine hydrochloride is present in mucopolysaccharides and in polysaccharides found in bacteria, fungi, higher plants has been used as a standard to quan...
Ouabain is a cardiac glycoside acting by Na(+)/K(+) ATPase, regulates transcription of MDR and MRP.
Dehydrocostus lactone and CL from root of S. lappa have anti-colorectal cancer activities through inhibiting Wnt/β-catenin pathway.