LDN-214117 - CAS 1627503-67-6
Catalog number:
1627503-67-6
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C25H29N3O3
Molecular Weight:
419.52
COA:
Inquire
Targets:
ALK
Description:
LDN-214117 is a selective and potent ALK2 inhibitor. LDN-214117 inhibited ALK2 most, with a biochemical IC50 of 24 nM. There are currently no effective therapies for fibrodysplasia ossificans progressiva (FOP), a debilitating and progressive heterotopic ossification disease caused by activating mutations of ACVR1 encoding the BMP type I receptor kinase ALK2. LDN-214117 shows a high degree of selectivity for ALK2 and low cytotoxicity that could provide a template for preclinical development.
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Purity:
>98%
Synonyms:
LDN-214117; LDN 214117; LDN214117
MSDS:
Inquire
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CAS 1627503-67-6 LDN-214117

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