LDC4297 - CAS 1453834-21-3
Category: Inhibitor
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Molecular Formula:
C23H28N8O
Molecular Weight:
432.52
COA:
Inquire
Targets:
CDK
Description:
LDC4297 is a potent and selective cyclin-dependent protein kinase 7 (CDK7) inhibitor with an IC50 of 0.13 nM.
Brife Description:
A novel and selective CDK7 inhibitor (IC50= 0.13 nM)
Synonyms:
2-piperidin-3-yloxy-8-propan-2-yl-N-[(2-pyrazol-1-ylphenyl)methyl]pyrazolo[1,5-a][1,3,5]triazin-4-amine; LDC4297; LDC-4297; LDC 4297; LCD044297; LCD-044297; LCD 044297.
Solubility:
DMSO: ≥60 mg/mL
Storage:
Store in a cool and dry place (or refer to the Certificate of Analysis).
MSDS:
Inquire
Density:
1.37±0.1 g/cm3
InChIKey:
LSGRZENCFIIHNV-UHFFFAOYSA-N
InChI:
1S/C23H28N8O/c1-16(2)19-15-27-31-21(19)28-23(32-18-8-5-10-24-14-18)29-22(31)25-13-17-7-3-4-9-20(17)30-12-6-11-26-30/h3-4,6-7,9,11-12,15-16,18,24H,5,8,10,13-14H2,1-2H3,(H,25,28,29)
Canonical SMILES:
CC(C)C1=C2N=C(N=C(N2N=C1)NCC3=CC=CC=C3N4C=CC=N4)OC5CCCNC5
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Chemical Structure

CAS 1453834-21-3 LDC4297

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