LCRF-0004 - CAS 1229611-73-7
Catalog number: 1229611-73-7
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
C28H18F4N6O2S
Molecular Weight:
578.55
COA:
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Targets:
c-Met/HGFR
Description:
This active molecular is a selective RON receptor tyrosine kinase inhibitor. The RON receptor tyrosine kinase has been reported that it usually overexpressed in the pancreatic cancer. Preclinical research shows that inhibition of RON function can decrease pancreatic cancer cell migration, invasion and survival and this can also sensitize pancreatic cancer cells to chemotherapy. RON receptor tyrosine kinase may become a potential therapeutic target for the pancreatic cancer.
Purity:
98%
Appearance:
Powder
Synonyms:
LCRF-0004; LCRF 0004; LCRF0004; N-(3-fluoro-4-((2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yl)oxy)phenyl)-1-phenyl-5-(trifluoromethyl)-1H-pyrazole-4-carboxamide
Solubility:
Soluble in DMSO
Storage:
-20°C Freezer
MSDS:
Inquire
Application:
pancreatic cancer
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Milligrams-Grams
Canonical SMILES:
O=C(C1=C(C(F)(F)F)N(C2=CC=CC=C2)N=C1)NC3=CC=C(OC4=C5C(C=C(C6=CN(C)C=N6)S5)=NC=C4)C(F)=C3
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