Lasiodonin - CAS 38602-52-7
Catalog number: 38602-52-7
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
C20H28O6
Molecular Weight:
364.43
COA:
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Chemical Family:
Diterpenoids
Description:
Lasiodonin is a natural diterpenoid compound found in several plants.
Purity:
>97%
Appearance:
Powder
Synonyms:
(1alpha,6beta,7alpha,11beta)-7,20-Epoxy-1,6,7,11-tetrahydroxy-kaur-16-en-15-one
MSDS:
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Quality Standard:
Enterprise Standard
Quantity:
Milligrams-Grams
Density:
1.4±0.1 g/cm3
1.Diterpenoids from Isodon japonica.
Zhang JX;Han QB;Zhao AH;Sun HD Fitoterapia. 2003 Jul;74(5):435-8.
A new ent-kaurane diterpenoid maoyecrystal F (1) and its acetonide derivative (2), together with seven known compounds, lasiodonin, maoyerabdosin, odonicin, enmenin, oridonin, beta-sitosterol and daucosterol, were isolated from the leaves of Isodon japonica.
2.Ent-kauranoids from Isodon rubescens var. taihangensis.
Han QB;Li RT;Li ML;Mou YK;Tian QE;Li SW;Sun HD J Asian Nat Prod Res. 2005 Feb;7(1):31-6.
Two new compounds, rubescensins Q and R (1 and 2), and a new acetonide derivative (3) of lasiodonin, together with thirteen known analogues, oridonin (4), ponicidin (5), wikstroemioidin B (6), lasiodonin (7), lasiokaurin (8), enmenol (9), 1-O-beta-D-glucopyranosyl-enmenol (10), trichokaurin (11), the acetonide of maoyecrystal F (12), rabdoternins A-D (13-16), have been isolated from Isodon rubescens var. taihangensis. The structures of the new compounds were elucidated on the basis of spectroscopic methods, especially the 2D NMR spectral analysis. Compound 3 exhibited cytotoxicity against K562, Bcap37, CA, CNE, BIU87, BGC823, and HeLa cell lines.
3.Ent-kaurane diterpenoids from Isodon rubescens var. lushanensis.
Han QB;Li ML;Li SH;Mou YK;Lin ZW;Sun HD Chem Pharm Bull (Tokyo). 2003 Jul;51(7):790-3.
Four new ent-kaurane diterpenoids lushanrubescensins F-I (1-4), together with 11 known ones, lasiodonin (5), oridonin (6), ponicidin (7), isodonoiol (8), isodonal (9), rabdosin B (10), rabdoternins A and B (11 and 12), enmenol (13), epinodosin (14), and inflexusin (15), were isolated from Isodon rubescens var. lushanensis, and the structures were elucidated by spectroscopic analysis. The inhibitory effect against the K562, Bcap37, BGC823, BIU87, CA, CNE, and Hela cell lines of compounds 3 and 5-10 were evaluated.
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