|Description||Lappaconite Hydrobromide is a kind of alkaloid extracted from Aconitum sinomontanum Nakai and has anti-inflammatory effects.|
GSK-114 is a selective TNNI3 Interacting Kinase (TNNI3K) inhibitor with IC50 of 25nM. GSK-114 shows significant bias for TNNI3K over B-Raf, exceptional broad sp...
Fagomine is an iminosugar originally isolated from seeds of buckwheat (Fagopyrum sculentum Moench). It presents in the human diet and is now available as a pure...
QS11 contains a planar purine ring with C2, C6, and N9-positions substituted. QS11, a GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) inhibitor...
Crotamiton is a general antipruritic agent for treating scabies.
Schisanhenol, isolated from Schisandra rubriflora, has antioxidative effect on human LDL oxidation. The mechanism of Schisanhenol against LDL oxidation may be t...
Guanidine HCl, the crystalline compound of strong alkalinity formed by the oxidation of guanine, is a normal product of protein metabolism and a protein denatur...
3PO, as a small molecule competitive inhibitor of HIF-1-induced PFKFB3 it has the potential to suppress tumor glucose metabolism and growth of non-small cell lu...
Mastoparan, a tetradecapeptide which is a component of wasp venom, activates Gi and Go and has been shown to cause an increase in the production of Arachidonic ...
Clodronate disodium tetrahydrate
Clodronate is a non-nitrogenous bisphosphonate that can bind to bone to reduce the bone resorption. It is used as an anti-osteoporotic drug for the prevention o...
Retinyl-β-D-glucoside is a naturally occurring and biologically active metabolites of vitamin A, which are found in fish and mammals.
Limaprost is a potent platelet adhesion inhibitor and vasodilator that increases blood flow and inhibits platelet aggregation. It is an analog of prostaglandin ...
SYR127063 is a selective HER2 inhibitor with IC50 value of 11 nM for HER2, and > 10000 nM for HER4. It can bind to HER2 in an active-like conformation.
Carotenoid pigment found mostly in animal organisms, but also occuring in plants; thought to be the precursor of astacin. Astaxanthin is a carotenoid pigment fo...
WWL 123 is an α/β-hydrolase domain 6 (ABHD6) inhibitor (IC50 = 0.43 μM) with antiepileptic activity. It suppresses PTZ-induced seizures in healthy mice and spon...
Ceramide is a potent modulator of cell proliferation and differentiation and it has been found to activate protein phosphatase-1 (PP1) and PP2A, as well as cera...
Aloe-emodin is an interferon-inducing agent with IC50 of about 1 μg/mL for JEV and of about 0.33 μg/mL for EV71.
Ginsenoside Rb3, a natural triterpenoid saponin, possesses the effect against isoproterenol-induced myocardial injury and heart function impairment, and that th...
Deoxynojirimycin inhibits mammalian glucosidase 1. As well, it inhibits intestinal and lysosmal alpha-glucosidases, beta-glucosidase from sweet almonds, pancrea...
The D-Tartrate salt form of Isofagomine, an imino pyranose compound, has been found to be a glucosylceramidase stimulant and could exhibit activity in Gaucher's...