|Description||Lafutidine, a newly developed histamine H(2)-receptor antagonist, inhibits gastric acid secretion.|
Imetit dihydrobromide is a potent and high affinity agonist at histamine H3 and H4 receptors (Ki = 0.3 and 2.7 nM, respectively). It induces an eosinophil shape...
Benzquinamide hydrochloride is an antiemetic compound with antihistaminic, anticholinergic and sedative properties. The mechanism of action is not quite sure an...
Aminopotentidine is a high selectivity and high affinity histamine H2 receptor antagonist. Its KB values are 220 and 280 nM at human and guinea pig H2 receptors...
Clemastine is a histamine H1 antagonist commonly used for the symptoms of allergic rhinitis, hay fever, and cold.
Iodophenpropit dihydrobromide is a selective and high affinity histamine H3 antagonist (KD = 0.3 nM).
Tripelennamine hydrochloride, the hydrochloride salt form of tripelennamine, is a blood-brain barrier penetrant and orally active H1-receptor antagonist. Tripel...
Amthamine dihydrobromide is the dihydrobromide salt of amthamine, which is a highly selective histamine H2 receptor agonist. It is a weak antagonist at H3 and h...
Bavisant is a highly selective, orally active antagonist of the human H3 receptor. It is a novel mechanism of action, involving wakefulness and cognition. It ha...
(R)-(-)-alpha-Methylhistamine dihydrobromide is a potent and high affinity histamine H3 agonist (KD = 50.3 nM) displaying > 200-fold selectivity over H4 recepto...
Fenspiride is an α adrenergic and H1 histamine receptor antagonist. It is an oxazolidinone spiro compound. It is used as a drug in the treatment of certain resp...
Clemastine Fumarate (Clemastine) is a selective histamine H1 receptor antagonist with IC50 of 3 nM.
Clemizole is an H1 antagonist acts as a TRPC5 channel blocker (IC50 values are 1.1, 6.4, 9.1, 11.3 and 26.5 μM for TRPC5, TRPC4, TRPC3, TRPC6 and TRPC7 respecti...
Ebrotidine(FI 3542), a competitive H2-receptor antagonist, has gastroprotective activity under the condition of gastric mucosal damage caused by some stress res...
Nizatidine is a histamine H2 receptor antagonist with IC50 of 0.9 nM, also inhibits AChE with IC50 of 6.7 μM.
A 331440 dihydrochloride
A 331440 dihydrochloride is a histamine H3 receptor antagonist (Ki = 21.7 and 22.7 nM for rat and human H3 receptors, respectively). A 331440 reduces weight in ...
Chlorcyclizine is a first-generation Histamine Receptor antagonist of the phenylpiperazine class. It can be used primarily to treat allergy symptoms such as rhi...
Hydroxyzine pamoate, a derivative of hydroxyzine, is a histamine H1-receptor antagonist that has been used as anxiolytic and antihistaminic so that it is probab...
Buclizine hydrochloride is an antihistamine and anticholinergic of the piperazine derivative family.
Diphenhydramine HCl (Benadryl), a histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a ...
GT 2016 is a high affinity and brain-penetrant histamine H3 receptor antagonist (Ki = 43.8 nM). It displays selectivity against H1 and H2 receptors (IC50 >10 μM...