L-Thyroxine sodium salt pentahydrate - CAS 6106-07-6
Catalog number:
6106-07-6
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C15H20I4NNaO9
Molecular Weight:
888.93
COA:
Inquire
Targets:
Others
Description:
L-Thyroxine sodium salt pentahydrate is an iodine containing hormone produced from thyroglobulin in the thyroid follicular cells. It reduces total cholesterol level, low-density lipoprotein cholesterol as well as waist to hip ratio in subclinical hypothyroidism pateints. It was also used to study the light-induced hormone conversion of T4 to T3 in regulation of photoperiodic response of gonads in Japanese quail.
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Purity:
>98%
Synonyms:
Sodium levothyroxine pentahydrate
MSDS:
Inquire
1.The effect of hydrocortisone, thyroxine, and phenobarbital on diamine oxidase activity in newborn rat intestine.
Karp WB, Robertson AF, Kanto WP Jr. Pediatr Res. 1987 Apr;21(4):368-70.
There is a reported association between administration of prenatal glucocorticoids and a decreased incidence of necrotizing enterocolitis in human infants. In rats, the degree of ischemic bowel disease correlates negatively with intestinal diamine oxidase (E.C. 1.4.3.6) activity. Since the administration of hydrocortisone, thyroxine, or phenobarbital to newborn rat pups affects the development of intestinal enzymes, we were interested in knowing whether hydrocortisone, thyroxine, or phenobarbital specifically affect intestinal diamine oxidase activity. We injected rat pups with hydrocortisone sodium succinate, 1-thyroxine pentahydrate, sodium salt, sodium phenobarbital, or the control solution on days 4, 6, 8, or 10 of life (phenobarbital, days 3, 5, 7, or 9). Pups were injected 3 days consecutively (phenobarbital, 4 days), and all were sacrificed on days 7, 9, 11, and 13. Intestinal diamine oxidase and intestinal invertase (E.C. 3.2.1.26) activities were measured.
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CAS 6106-07-6 L-Thyroxine sodium salt pentahydrate

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