L-Thyroxine - CAS 51-48-9
Catalog number: 51-48-9
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C15H11I4NO4
Molecular Weight:
776.87
COA:
Inquire
Targets:
Others
Description:
L-Thyroxine is a synthetic form of thyroxine and a hormone replacement drug.
Publictions citing BOC Sciences Products
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Purity:
>98%
Synonyms:
NSC 36397
MSDS:
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1.Effect of Prolonged Iodine Overdose on Type 2 Iodothyronine Deiodinase Ubiquitination-Related Enzymes in the Rat Pituitary.
Zhang X1, Jiang Y1, Han W1, Liu A1, Xie X1, Han C1, Fan C1, Wang H1, Zhang H1, Ding S1, Shan Z1, Teng W2. Biol Trace Elem Res. 2016 May 7. [Epub ahead of print]
The purpose of this study is to determine the effect of prolonged iodine overdose on type 2 iodothyronine deiodinase (D2) ubiquitination-related enzymes. Male Wistar rats were fed different doses of iodine and were then euthanized at the 4, 8, 12, or 24 weeks (4w, 8w, 12w, or 24w) after iodine administration. Urinary iodine concentration (UIC), thyroid-stimulating hormone (TSH), total thyroxine (TT4), and total triiodothyronine (TT3) were determined. Real-time quantitative RT-PCR and Western blot were used to measure mRNA and protein expression levels of pituitary D2 as well as two D2-specific ubiquitin ligases [WD repeat and SOCS box-containing protein 1 (WSB-1), membrane-associated ring finger (C3HC4) 6 (MARCH6 or TEB4)] and two D2-specific deubiquitinating enzymes [ubiquitin-specific peptidase 20 (USP20) and ubiquitin-specific peptidase 33 (USP33)]. The mRNA and protein expression levels of USP19, a TEB4-specific deubiquitinating enzyme, were also measured.
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CAS 51-48-9 L-Thyroxine

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