L-152,804 - CAS 6508-43-6
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
C23H26O4
Molecular Weight:
366.46
COA:
Inquire
Targets:
Neuropeptide Y receptor
Description:
L-152,804 is a potent and selective orally available non-peptide neuropeptide Y Y5 receptor antagonist with Ki value of 26 nM for hY5. It displays > 300-fold selectivity over hY1, hY2, and hY4 receptors. It is centrally active upon oral administration in vivo. It causes weight loss in diet-induced obese mice by inducing a potent reduction of food intake in rodents.
Purity:
≥99% by HPLC
Synonyms:
L-152,804; L 152,804; L152,804; 5,5-Dimethyl-2-(2,3,4,9-tetrahydro-3,3-dimethyl-1oxo-1H-xanthen-9-yl)-1,3-cyclohexanedione; 9-(4,4-Dimethyl-2,6-dioxocyclohexyl)-1,2,3,4-tetrahydro-3,3-dimethyl-1-xanthenone; 9-(2-Hydroxy-4,4-dimethyl-6-oxo-1-cyclohexenyl)-3,3-dimethyl-4,9-dihydro-2H-xanthen-1-one; L-152804; L152804
MSDS:
Inquire
InChIKey:
XQDXIHYKAGHZRX-UHFFFAOYSA-N
InChI:
InChI=1S/C23H26O4/c1-22(2)9-14(24)20(15(25)10-22)19-13-7-5-6-8-17(13)27-18-12-23(3,4)11-16(26)21(18)19/h5-8,19-20H,9-12H2,1-4H3
Canonical SMILES:
CC1(CC(=O)C(C(=O)C1)C2C3=CC=CC=C3OC4=C2C(=O)CC(C4)(C)C)C
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Neuropeptide Y receptor Products


CAS 313988-89-5 [cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide

[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPan
(CAS: 313988-89-5)

A Y5 receptor-selective agonist (IC50 values for inhibition of NPY binding to human Y5, Y1, Y2 and Y4 receptors are 0.24, 530, > 500, and 51 nM respectively, Ki...

CAS 186185-03-5 BMS-193885

BMS-193885
(CAS: 186185-03-5)

BMS-193885 is a potent and selective neuropeptide Y1 receptor antagonist with IC50= 5.9nM, Ki = 3.3 nM. BMS-193885 displays > 47, > 100, > 160, > 160 and > 160-...

CAS 439861-56-0 NPY 5RA972

NPY 5RA972
(CAS: 439861-56-0)

NPY5RA972 is a neuropeptide Y Y5 antagonist.

CAS 1383478-94-1 CYM 9484

CYM 9484
(CAS: 1383478-94-1)

CYM 9484 has been found to be an effective neuropeptide Y (NPY) Y2 receptor antagonist.

CAS 158859-98-4 GR 231118

GR 231118
(CAS: 158859-98-4)

GR 231118 is a potent neuropeptide Y (NPY) Y1 receptor antagonist (pA2 = 10 and 10.5 at rY1 and hY1 receptors, respectively) and an NPY Y4 receptor agonist (pEC...

CAS 132699-73-1 [Leu31,Pro34]-Neuropeptide Y (human, rat)

[Leu31,Pro34]-Neuropeptide Y (human, rat
(CAS: 132699-73-1)

[Leu31,Pro34]-Neuropeptide Y (human, rat) is a high affinity neuropeptide Y Y1 receptor agonist (Ki = 0.39 nM).

CAS 126339-09-1 Peptide YY (3-36)

Peptide YY (3-36)
(CAS: 126339-09-1)

Peptide YY (3-36) is a Y2/Y5 Neuropeptide Y receptor agonist (IC50= 0.11 nM for inhibition of 125I-PYY binding to Y2 receptor). Human peptide YY (PYY) has roles...

CAS 1094873-14-9 JNJ-31020028

JNJ-31020028
(CAS: 1094873-14-9)

JNJ-31020028 is a selective brain penetrant small molecule antagonist of the neuropeptide Y Y(2) receptor. JNJ-31020028 bound with high affinity (IC50 = 8.07, h...

Chemical Structure

CAS 6508-43-6 L-152,804

Quick Inquiry

Verification code

Featured Items