KN 93 - CAS 1188890-40-5
Category: Inhibitor
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Molecular Formula:
C26H29ClN2O4S
Molecular Weight:
501.04
COA:
Inquire
Targets:
CaMK-II
Description:
KN 93 is an inhibitor of multifunctional Calmodulin-dependent protein kinase (CaMKII; Ki value 0.37 μM for inhibition of CaMKII phosphorylating activity). KN93 also affects CaV1.3 and CaV1.2 calcium channels in a CaMKII-independent manner.
Brife Description:
CaMK-II inhibitor
Purity:
99%
Synonyms:
Methoxybenzene-sulfonamide; N-[2-[[[(E)-3-(4-chlorophenyl)prop-2-enyl]-methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4-methoxybenzenesulfonamide
MSDS:
Inquire
Melting Point:
59-60 ºC
Density:
1.288±0.06 g/cm3
InChIKey:
LLLQTDSSHZREGW-AATRIKPKSA-N
InChI:
InChI=1S/C26H29ClN2O4S/c1-28(17-5-6-21-9-11-23(27)12-10-21)20-22-7-3-4-8-26(22)29(18-19-30)34(31,32)25-15-13-24(33-2)14-16-25/h3-16,30H,17-20H2,1-2H3/b6-5+
Canonical SMILES:
CN(CC=CC1=CC=C(C=C1)Cl)CC2=CC=CC=C2N(CCO)S(=O)(=O)C3=CC=C(C=C3)OC
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Chemical Structure

CAS 1188890-40-5 KN 93

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