KN-92 - CAS 176708-42-2
Catalog number: 176708-42-2
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C24H25ClN2O3S
Molecular Weight:
456.98
COA:
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Targets:
CaMK-II
Description:
KN-92 is intended to be used as a control compound in studies designed to elucidate the antagonist activities of KN-93. KN-93 inhibits histamine-induced aminopyrine uptake in parietal cells (IC50 = 300 nM). KN-93 has been used to implicate roles for CaMKII in Ca2+-induced Ca2+ release in cardiac myocytes, constitutive phosphorylation of 5-lipoxygenase in 3T3 cells, and Ca2+-dependent activation of HIF-1α in colon cancer cell.
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Purity:
>98%
Synonyms:
KN 92; KN92
MSDS:
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