|Description||KF58333 is a novel derivative of radicicol, binds to the Hsp90 chaperone machinery, depletes p210Bcr-Abl and Raf-1 proteins followed by induction of erythroid differentiation and G1 phase accumulation, and induces apoptosis in human CML cells.|
|Brife Description||KF58333 is a novel Hsp90 inhibitor.|
|Synonyms||6H-Oxireno[e]benzoxacyclotetradecin-6,12(7H)-dione, 8-chloro-1a,14,15,15a-tetrahydro-9,11-dihydroxy-14-methyl-, 6-[O-[2-(2-oxo-1-pyrrolidinyl)ethyl]oxime], (1aR,2Z,4E,6E,14R,15aR)- (9CI)|
|Storage||3 years -20oC powder, 6 months-80oC in solvent.|
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