|Description||Kebuzone is a non-steroidal anti-inflammatory drug. It also has analgesic, antipyretic, and platelet-inhibitory activities. Kebuzone is a cyclooxygenase inhibitor. It can block the synthesis of prostaglandins by inhibiting cyclooxygenase.|
|Appearance||Off-White to Light Yellow Solid|
|Synonyms||4-(3-Oxobutyl)-1,2-diphenyl-3,5-pyrazolidinedione; 1,2-Diphenyl-4-(2-acetylethyl) pyrazolidine-3,5-dione; Chebutan; Chepirol; Chetazol; Chetazolidin; Chetil; Chetopir; Copirene; Ejor; Gammachetone; KPB; Ketanol; Ketason; Ketazon; Ketazone; Ketophenylbutazone; Pecnon; Phloguron; Recheton; Reuchetal; γ-Ketazone; γ-Ketophenylbutazone; γ-Oxophenylbutazone;|
|Solubility||Chloroform (Slightly), Ethyl Acetate (Slightly)|
|Application||non-steroidal anti-inflammatory drug.|
|Quality Standard||In-house standard|
|Shelf Life||2 month in rt, long time|
|Boiling Point||No Data Available|
|Melting Point||>85℃ (dec.)|
|Current Developer||Originator Marrindale|
Naproxcinod, a nitro compound, has been found to be a nitric oxide donor as well as a cyclooxygenase inhibitor that was once studied aginast duchenne muscular d...
A competitive inhibitor of COX-1 and COX-2
Indoprofen, a non-steroidal anti-inflammatory drug, is a cyclooxygenase inhibitor and used for the treatment of pain and inflammation and spinal muscular atroph...
Gingerol is the active constituent of fresh ginger. It is bioactive compound found in ginger (Zingiber officinale) with antioxidant activity, which functions as...
Loxoprofen is a non-steroidal anti-inflammatory drug in the propionic acid derivatives group, which also includes ibuprofen and naproxen among others. It is a n...
A non-steroidal COX-1/COX-2 inhibitor; A nonsteroidal anti-inflammatory drug
Triflusal irreversibly inhibits the production of thromboxane-B2 in platelets by acetylating cycloxygenase-1.
A highly selective COX-2 inhibitor
A selective COX-2 inhibitor
Bufexamac is a COX inhibitor for IFN-α release with EC50 of 8.9 μM.Bufexamac is a drug used as an anti-inflammatory agent on the skin, as well as rectally. Comm...
A non-selective COX inhibitor with IC50 of 60 and 220 nM for ovine COX-1 and -2, respectively.
Pravadoline is a COX inhibitor and cannabinoid CB agonist used as an anti-inflammatory and analgesic agent. It inhibits prostaglandin synthesis, and it also sup...
Vedaprofen is a nonsteroidal anti-inflammatory drug (NSAID) commonly used in veterinary medicine.
An inhibitor of Cox-1 and Cox-2；A nonsteroidal anti-inflammatory drug
A non-selective COX inhibitor with IC50 of 0.5 μg/ml and 0.5 μg/ml for COX-1 and -2 in intact cells, respectively
The prodrug Parecoxib as well as its active metabolite val have a specific affinity to the cannabinoid (CB) receptor measured in CB1-expressing HEK 293 cells an...
A COX-2 inhibitor( IC50s = 26 nM and > 50 µM in human osteosarcoma cells )
Diclofenac diethylamine is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.
Deracoxib is a non-steroidal anti-inflammatory drug (NSAID) of the coxib class. Deracoxin is a selective cyclooxygenase-2 (COX-2) inhibitor used in the treatmen...
Dexibuprofen is a Cyclooxygenase inhibitor originated by Gebro Pharma GmbH. It is a non-steroidal anti-inflammatory drug as the active dextrorotatory enantiomer...