Catalog number: B0084-284866
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
Molecular Weight:
Histone Demethylase
KDM5-inhibitor is an analog of CPI-455, a selective KDM5 inhibitor. CPI-455 increases levels of H3K4 trimethylation (H3K4me3) and decreases the number of DTPs in multiple cancer cell lines treated with standard chemotherapy or targeted agents. It reduces survival of drug-tolerant cancer cells.
Ordering Information
Catalog Number Size Price Stock Quantity
B0084-284866 10 mg $198 In stock
Bulk Inquiry
Canonical SMILES:
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Histone Demethylase Products

CAS 199596-24-2 (Z)-JIB-04

(CAS: 199596-24-2)

(Z)-JIB-04 is a Z-isomer of JIB-04, which is a small-molecule histone demethylase inhibitor with antitumor activity. JIB-04 selectively inhibits tumor growth vi...

CAS 1394854-52-4 GSK-J2

(CAS: 1394854-52-4)

GSK-J2, a benzazepin derivative, has been found to have poor activity as a JMJD3 inhibitor so that could be used in the biological study of GSK-J1 as a negative...

CAS 1628210-26-3 KDM5-IN-1

(CAS: 1628210-26-3)

KDM5-IN-1 is a potent and selective KDM5 inhibitor with modest cell activity (PC9 H3K4Me3 EC50 = 5.2 μM).


KDM5-inhibitor is an analog of CPI-455, a selective KDM5 inhibitor. CPI-455 increases levels of H3K4 trimethylation (H3K4me3) and decreases the number of DTPs i...

CAS 2003260-55-5 NCGC00244536

(CAS: 2003260-55-5)

NCGC00244536 is a potent KDM4A inhibitor (IC50= 10 nM) that inhibits the in vivo growth of tumors derived from PC3 cells and ex vivo human PCa explants.

CAS 1379573-88-2 CBB1003

(CAS: 1379573-88-2)

CBB1003, a piperazine derivative, has been found to be a histone demethylase LSD1 inhibitor that could restrain the proliferation and colony formation of CRC ce...

CAS 1628214-07-2 CPI 4203

CPI 4203
(CAS: 1628214-07-2)

CPI 4203 is a selective inhibitor of KDM5 demethylases structurally related to CPI 455.

CAS 5852-78-8 IOX1

(CAS: 5852-78-8)

IOX1 is a potent and broad-spectrum inhibitor of 2OG oxygenases.

CAS 1222800-79-4 ML324

(CAS: 1222800-79-4)

ML324 exhibits good Caco-2 cell permeability, and possesses excellent microsomal stability in the presence of both mouse and rat liver microsomes.

CAS 1788896-33-2 NL-103

(CAS: 1788896-33-2)

NL-103, a nicotinamide derivative, has been found to be an inhibitor of both histone deacetylases and hedgehog pathway. It was found to exhibit activity in decr...

CAS 1401966-69-5 GSK2879552

(CAS: 1401966-69-5)

GSK2879552 has been found to be a LSD1 inhibitor that could have antineoplastic effect through restraining the growth of overexpressed tumor cells. It was just ...

CAS 1373422-53-7 GSK J1

(CAS: 1373422-53-7)

GSK-J1 is a highly potent H3K27 histone demethylase inhibitor with IC50 of 28 nM and 53 nM in cell-free assays for JMJD3 (KDM6B) and UTX (KDM6A), respectively, ...

CAS 1453071-47-0 TC-E 5002

TC-E 5002
(CAS: 1453071-47-0)

TC-E 5002 is a selective histone demethylase KDM2/7 subfamily inhibitor (IC50 = 0.2, 1.2, 6.8, 55, 83, >100 and >120 μM for KDM7A, KDM7B, KDM2A, KDM5A, KDM4C, K...

CAS 708991-09-7 YUKA1

(CAS: 708991-09-7)

YUKA1 is a cell-permeable inhibitor of lysine demethylase 5A (KDM5A/RBP2/JARID1A) (IC50 value 2.66 μM). YUKA1 inhibits drug resistance and cancer cell growth in...

CAS 1379573-92-8 CBB1007

(CAS: 1379573-92-8)

CBB1007, an amidino-guanidinium derivative, has been found to have biological activity in anticancer-study by acting as a LSD1 inhibitor. IC50: 5.27 uM.

ML 324 dihydrochloride

ML 324 dihydrochloride is an inhibitor of Jumonji domain-containing protein 2 (JMJD2) histone demethylase. It potently suppresses herpes simplex virus (HSV) IE ...

CAS 1373423-53-0 GSK J4 HCl

(CAS: 1373423-53-0)

GSK J4 HCl is a cell permeable prodrug of GSK J1, which is the first selective inhibitor of the H3K27 histone demethylase JMJD3 and UTX with IC50 of 60 nM and i...

CAS 1628208-23-0 CPI 455

CPI 455
(CAS: 1628208-23-0)

CPI 455 is a selective inhibitor of KDM5 demethylases (IC50 value 10 nM for inhibition of full length KDM5A) that specifically alters H3K4 methylation (H3K4me3)...

DDP-38003 trihydrochloride

DDP-38003 trihydrochloride is the trihydrochloride salt of DDP-38003 which is a potent, selective, oral bioavailable irreversible inhibitor of KDM1A.

CAS 1616392-22-3 GSK3326595

(CAS: 1616392-22-3)

GSK3326595, also called as EPZ015938, is an orally available and specific inhibitor of protein arginine methyltransferase 5 (PRMT5) that potently inhibits tumor...

Chemical Structure

CAS  KDM5-inhibitor

Quick Inquiry

Verification code

Featured Items