KC7F2 - CAS 927822-86-4
Catalog number:
927822-86-4
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C16H16Cl4N2O4S4
Molecular Weight:
570.38
COA:
Inquire
Targets:
HIF/HIF Prolyl-Hydroxylase
Description:
KC7F2 is a selective HIF-1α transcription inhibitor with IC50 of 20 μM in a cell-based assay.
Publictions citing BOC Sciences Products
  • >> More
Purity:
98%
Appearance:
Solid powder
Solubility:
DMSO,100mg/mL(175.32mM);Water,<1mg/mL(<1mM);Ethanol,<1mg/mL(<1mM)
Storage:
3 years -20℃powder;6 months-80℃in solvent
MSDS:
Inquire
Shelf Life:
2 years if stored properly
Canonical SMILES:
ClC1=C(S(NCCSSCCNS(C2=C(Cl)C=CC(Cl)=C2)(=O)=O)(=O)=O)C=C(Cl)C=C1
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related HIF/HIF Prolyl-Hydroxylase Products


THS-044
(CAS: 62054-67-5)

THS-044 binding stabilizes the HIF2α PAS-B folded state, for regulating HIF2 activity in endogenous and clinical settings.

PT-2385
(CAS: 1672665-49-4)

PT-2385 is a small molecule inhibitor with oral activity that inhibits hypoxia inducible factor (HIF)-2alpha heterodimerization and its subsequent binding to DN...

JNJ-42041935
(CAS: 1193383-09-3)

JNJ-42041935 is a potent (pK(I) = 7.3-7.9), 2-oxoglutarate competitive, reversible, and selective inhibitor of PHD enzymes. JNJ-42041935 is a new pharmacologica...

CAS 362-07-2 2-methoxyestradiol

2-methoxyestradiol
(CAS: 362-07-2)

2-methoxyestradiol, also known as 2-ME, is an orally bioavailable estradiol metabolite with potential antineoplastic activity. 2-Methoxyestradiol inhibits angio...

CAS 685898-44-6 PX-478

PX-478
(CAS: 685898-44-6)

PX-478 is HIF-1alpha inhibitor, is also an orally active small molecule with potential antineoplastic activity. Although its mechanism of action has yet to be ...

CAS 808118-40-3 Roxadustat (FG-4592)

Roxadustat (FG-4592)
(CAS: 808118-40-3)

Roxadustat (FG-4592) is an HIF α prolyl hydroxylase inhibitor, stabilizes HIF-2 and induces EPO production.

CAS 931398-72-0 IOX2

IOX2
(CAS: 931398-72-0)

CAS 327-97-9 Chlorogenic Acid

Chlorogenic Acid
(CAS: 327-97-9)

Chlorogenic acid is a hydroxycinnamic acid and a member of a family of naturally occurring organic compounds.

CAS 1187990-87-9 MK-8617

MK-8617
(CAS: 1187990-87-9)

MK-8617 is a potent and selective pan-inhibitor of Hypoxia-inducible factor prolyl hydroxylase 1−3 (HIF PHD1−3) (PHD1: IC50 = 1.0 nM; PHD2: IC50 =1.0nM; PHD3: I...

FG-2216
(CAS: 223387-75-5)

FG-2216, also known as YM311, is orally bioavailable HIF-prolyl hydroxylase inhibitor. FG-2216 induced significant and reversible Epo induction in vivo.

DASA-58
(CAS: 1203494-49-8)

DASA-58 is a specific and potent Pyruvate kinase M2 (PKM2) activator.

CAS 89464-63-1 DMOG

DMOG
(CAS: 89464-63-1)

DMOG is an antagonist of α-ketoglutarate cofactor and inhibitor for HIF prolyl hydroxylase.

CAS 1357171-62-0 ML228

ML228
(CAS: 1357171-62-0)

HIF pathway activator (EC50 values are 1.23 and 1.4 μM for HRE gene reporter assay and HIF-1α nuclear translocation assay respectively); acts via chelation of i...

CAS 64224-21-1 Oltipraz

Oltipraz
(CAS: 64224-21-1)

Oltipraz, a promising cancer chemopreventive agent, is a bifunctional inducer, modulating both phase I and II drug-metabolizing enzymes to enhance carcinogen de...

CAS 1154028-82-6 Molidustat

Molidustat
(CAS: 1154028-82-6)

Molidustat, also known as BAY 85-3934, is a novel inhibitor of hypoxia-inducible factor (HIF) prolyl hydroxylase (PH) which stimulates erythropoietin (EPO) prod...

Daprodustat
(CAS: 960539-70-2)

Daprodustat, also known as GSK1278863, is a novel HIF-prolyl hydroxylase inhibitor. Hypoxia inducible factor (HIF) stabilization by HIF-prolyl hydroxylase (PHD)...

CAS 1227158-85-1 BAY 87-2243

BAY 87-2243
(CAS: 1227158-85-1)

BAY 87-2243 inhibits HIF-1 reporter gene activity and CA9 protein expression with IC50 of 0.7 nM and 2 nM, respectively.

KC7F2
(CAS: 927822-86-4)

KC7F2 is a selective HIF-1α transcription inhibitor with IC50 of 20 μM in a cell-based assay.

Quick Inquiry

Verification code

Featured Items