K134 - CAS 189362-06-9
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C22H29N3O4
Molecular Weight:
399.48
COA:
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Targets:
Phosphodiesterase (PDE)
Description:
K134 is a selective phosphodiesterase 3 (PDE3) inhibitor, and has been shown to exhibit more potent anti-platelet activity than cilostazol. In vivo studies have demonstrated the anti-thrombotic and anti-hyperplastic effects of K-134, and that these effects of K-134 are stronger than those of cilostazol.
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Synonyms:
1-cyclopropyl-1-[(1R,2R)-2-hydroxycyclohexyl]-3-[3-[(2-oxo-1H-quinolin-6-yl)oxy]propyl]urea; 6-(3-(3-cyclopropyl-3-(2-hydroxycyclohexyl)ureido)propoxy)-2(1H)-quinolinone; K 134 compound; K-134 compound; K134 compound; OPC 33509; OPC-33509; K-134
Storage:
Store in a cool and dry place (or refer to the Certificate of Analysis).
MSDS:
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Boiling Point:
731.4±60.0 ℃ at 760 Torr
Density:
1.29±0.1 g/cm3
InChIKey:
ULGNGSQNNMKROG-WOJBJXKFSA-N
InChI:
1S/C22H29N3O4/c26-20-5-2-1-4-19(20)25(16-7-8-16)22(28)23-12-3-13-29-17-9-10-18-15(14-17)6-11-21(27)24-18/h6,9-11,14,16,19-20,26H,1-5,7-8,12-13H2,(H,23,28)(H,24,27)/t19-,20-/m1/s1
Canonical SMILES:
C1CCC(C(C1)N(C2CC2)C(=O)NCCCOC3=CC4=C(C=C3)NC(=O)C=C4)O
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CAS 189362-06-9 K134

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