K-115 - CAS 223645-67-8
Catalog number:
223645-67-8
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C15H18FN3O2S
Molecular Weight:
323.39
COA:
Inquire
Targets:
ROCK
Description:
K-115, also called as Ripasudil or Glanatec, a selective ROCK inhibitor (IC50 =31 nM), is a promising emerging antiglaucoma drug, and was thus approved by the Japanese administrative authority in 2014.
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Appearance:
Solid powder
Synonyms:
4-fluoro-5-[[(2S)-2-methyl-1,4-diazepan-1-yl]sulfonyl]isoquinoline Glanatec K-115 K115 compound ripasudil
Solubility:
Soluble in DMSO
Storage:
Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -83℃ for long term (months to years).
MSDS:
Inquire
Shelf Life:
2 years
Boiling Point:
497.2±55.0 °C | Condition: Press: 760 Torr
Density:
1.293±0.06 g/cm3
InChIKey:
QSKQVZWVLOIIEV-NSHDSACASA-N
InChI:
1S/C15H18FN3O2S/c1-11-8-17-6-3-7-19(11)22(20,21)14-5-2-4-12-9-18-10-13(16)15(12)14/h2,4-5,9-11,17H,3,6-8H2,1H3/t11-/m0/s1
Canonical SMILES:
CC1CNCCCN1S(=O)(=O)C2=CC=CC3=CN=CC(=C32)F
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