K 01-162 - CAS 677746-25-7
Catalog number:
677746-25-7
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C15H14BrN
Molecular Weight:
288.19
COA:
Inquire
Targets:
Amyloid-β | γ-secretase
Description:
K 01-162 binds and destabilizes AβO (β-amyloid( EC50= 0.080 mM; IC50= 80 nM), can reduce the brain amyloid burden that exists in both fibrillar and RIPA-soluble, non-fibrillar forms.
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Purity:
≥98%
Appearance:
Solid Powder
Synonyms:
7-bromo-N,N-dimethyl-9H-fluoren-2-amine; 9H-Fluoren-2-aMine, 7-broMo-N,N-diMethyl-;
Solubility:
Soluble in DMSO
Storage:
Store at -20 °C
MSDS:
Inquire
Application:
Stabilizes hydrophobic core I of Aβ42 peptide (residues 17-21) to its α-helical conformation by interacting specifically in this region. in vivo
Quality Standard:
Enterprise Standard
Shelf Life:
As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly
Quantity:
Milligrams-Grams
InChIKey:
KABXKWWJTYSDTD-UHFFFAOYSA-N
InChI:
1S/C15H14BrN/c1-17(2)13-4-6-15-11(9-13)7-10-8-12(16)3-5-14(10)15/h3-6,8-9H,7H2,1-2H3
Canonical SMILES:
CN(C)C1=CC2=C(C=C1)C3=C(C2)C=C(C=C3)Br
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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Chemical Structure

CAS 677746-25-7 K 01-162

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