|Description||JW 67 has been found to be a new antagonist of canonical Wnt signaling and exhibit activities in restraining growth and downregulated Wnt target genes in human colorectal cancer cells.|
|Purity||≥97% by HPLC|
|Synonyms||JW 67; JW 67; JW 67; Trispiro[3H-indole-3,2'-[1,3]dioxane-2'',3'''-[3H]indole]-2,2'''(1H,1'''H)-dione|
KY1220 is a novel inhibitor of the Wnt/ß-catenin pathway, destabilizing both β-catenin and Ras via targeting the Wnt/β-catenin pathway (IC50= 2.1 μM in HEK293 r...
ICG-001 antagonizes Wnt/β-catenin/TCF-mediated transcription and specifically binds to element-binding protein (CBP) with IC50 of 3 μM, but is not the related t...
JW 67 has been found to be a new antagonist of canonical Wnt signaling and exhibit activities in restraining growth and downregulated Wnt target genes in human ...
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