|Description||JTE522, a selective COX-2 inhibitor, can induce apoptosis and inhibit cell proliferation in human endometrial cancer cell line RL95-2 cells and to explore the molecular mechanisms.|
|Synonyms||4-(4-cyclohexyl-2-methyl-1,3-oxazol-5-yl)-2-fluorobenzenesulfonamide; 4-(4-cyclohexyl-2-methyloxazol-5-yl)-2-fluorobenzenesulfonamide; JTE 522; JTE-522|
|Storage||Store in a cool and dry place (or refer to the Certificate of Analysis).|
|Boiling Point||500.6±60.0 ℃ at 760 Torr|
|Melting Point||166-167 ℃|
A COX-2 inhibitor( IC50s = 26 nM and > 50 µM in human osteosarcoma cells )
Flumizole is a non-steroidal anti-inflammatory drug (NSAID) that acts via inhibition of the enzyme cyclooxygenase (COX).
A non-steroidal COX-1/COX-2 inhibitor; A nonsteroidal anti-inflammatory drug
JTE522, a selective COX-2 inhibitor, can induce apoptosis and inhibit cell proliferation in human endometrial cancer cell line RL95-2 cells and to explore the m...
A COX inhibitor for COX-1 and COX-2 with IC50 of 8.7 μM and 5.2 μM, respectively.
A cyclooxygenase (COX) inhibitor
A selective COX-2 inhibitor
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A non-selective COX inhibitor of COX-1 and COX-2 with IC50 of 1.23 μM and 3.50 μM, respectively
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FR 122047 hydrochloride
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An inhibitor of COX-1 and COX-2
Bufexamac is a COX inhibitor for IFN-α release with EC50 of 8.9 μM.Bufexamac is a drug used as an anti-inflammatory agent on the skin, as well as rectally. Comm...
A nonselective COX1 and COX2 inhibitor with IC50 of 0.1 μg/mL and 5 μg/mL, respectively