|Description||JTC-801 is a selective opioid receptor-like1 (ORL1) receptor antagonist with IC50 of 94 nM, weakly inhibits receptors δ, κ, and μ. It is an opioid analgesic drug used in scientific research.|
ICI 199,441 hydrochloride
ICI 199,441 hydrochloride is the hydrochloride salt of ICI 199,441, which is a selective and highly potent κ agonist. It is 146-fold more active than U-50488 in...
N-MPPP Hydrochloride is a high affinity and selective agonist of the κ opioid receptor (KOR-1) with no measured binding at μ or δ sites.
6'-GNTI dihydrochloride is a potent and selective κ/δ-opioid heterodimer receptor agonist (EC50 = 39.8, 112.5 and > 1000 nM for κ/δ, κ/μ and δ/μ, respectively) ...
SB 205607 dihydrobromide
SB 205607 dihydrobromide is the first described non-peptide δ1 opioid receptor agonist with high affinity and selectivity for the δ1 subtype (Ki = 1.12, 2320 an...
SB 612111 hydrochloride
SB 612111 hydrochloride is a selective NOP receptor antagonist (Ki = 0.33, 57.6, 160.5 and 2109 nM for NOP, μ-, κ- and δ-receptors, respectively). SB 612111 exh...
ICI 174,864 is a potent and highly selective δ opioid antagonist. It shows partial agonist in vitro activity at δ receptors at high concentrations.
[Leu5]-Enkephalin is an endogenous opioid agonist peptide with morphine-like activity. It inhibits electrically stimulated contractions in mouse vas deferens (I...
ICI 154,129 is a selective δ opioid antagonist. It is a peptide analog that antagonized the effects of Leu-enkephalin.
Nor-Binaltorphimine dihydrochloride is a potent and selective kappa opioid receptor antagonist.
DIPPA hydrochloride is an irreversible and selective antagonist of κ-opioid receptor (KOR).
Trimebutine is an opioid receptor agonist used as spasmolytic agent abdominal pain.
ML 190 is a κ opioid receptor antagonist with IC50 value of 120 nM.
DAMGO is a highly selective peptide agonist of the μ opioid receptor.
ICI 204,448 hydrochloride
ICI 204,448 hydrochloride is the hydrochloride salt of ICI 204,448, which is a peripherally acting κ opioid receptor agonist. It does not cross the blood-brain ...
Igmesine is a selective σ1 receptor ligand (KD = 19.1 nM), with nearly no activity at σ2 receptors (IC50 > 1000 nM). It was developed by Pfizer. Igmesine inhibi...
CTAP has been found to be a selective μ-opioid receptor antagonist.
Meptazinol is a unique centrally active opioid analgesic, which inhibits [3H]-dihydromorphine binding with IC50 of 58 nM.
LY-2456302, also called as CERC-501, is a potent, highly selective and centrally-penetrant kappa opioid receptor antagonist(Ki= 0.807 nM)with favorable pharmaco...
PD-117302, a new nonpeptide opioid compound, is a selective kappa-opioid agonist. It has been evaluated in vivo for antinociceptive activity and other effects c...
BMS 986187 is a potent and selective δ-opioid receptor positive allosteric modulator (EC50 = 30 nM) exhibiting 100-fold selectivity for δ over μ-opioid receptor...