JPH203 - CAS 1037592-40-7
Catalog number:
1037592-40-7
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C23H19Cl2N3O
Molecular Weight:
472.32
COA:
Inquire
Targets:
Others
Description:
JPH203 is a potent and selective L-type amino acid transporter 1 (LAT1) inhibitor. It inhibits 14C-leucine uptake and cell growth in human colon cancer-derived HT-29 cells in vitro. It also inhibits 14C-leucine uptake in mouse renal proximal tubule cells expressing l-type amino acid transporter 1, and inhibits cell growth. It completely inhibits the proliferation of YD-38 cells in a dose- and time-dependent manner. It suppresses proliferation in cancer cell lines and is used for cancer research. It was developed by J-Pharma and in clinic phase 1 trials.
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Purity:
>98 %
Appearance:
White to off-white solid powder
Synonyms:
KYT-0353;KYT0353;JPH-203;(S)-2-amino-3-(4-((5-amino-2-phenylbenzo[d]oxazol-7-yl)methoxy)-3,5-dichlorophenyl)propanoic acid
Solubility:
Slightly soluble in DMSO, not soluble in water. Soluble in 5% hydrochloride
Storage:
-20°C Freezer
MSDS:
Inquire
Application:
JPH203 suppresses proliferation in cancer cell lines and is used for cancer research.
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Grams to Kilograms
Boiling Point:
672.0±55.0 °C | Condition: Press: 760 Torr
Density:
1.458±0.06 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr
Current Developer:
JPH203 was developed by J-Pharma and in clinic phase 1 trials.
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