|Description||JPH203 is a potent and selective L-type amino acid transporter 1 (LAT1) inhibitor. It inhibits 14C-leucine uptake and cell growth in human colon cancer-derived HT-29 cells in vitro. It also inhibits 14C-leucine uptake in mouse renal proximal tubule cells expressing l-type amino acid transporter 1, and inhibits cell growth. It completely inhibits the proliferation of YD-38 cells in a dose- and time-dependent manner. It suppresses proliferation in cancer cell lines and is used for cancer research. It was developed by J-Pharma and in clinic phase 1 trials.|
|Appearance||White to off-white solid powder|
|Solubility||Slightly soluble in DMSO, not soluble in water. Soluble in 5% hydrochloride|
|Application||JPH203 suppresses proliferation in cancer cell lines and is used for cancer research.|
|Quality Standard||In-house standard|
|Shelf Life||2 month in rt, long time|
|Quantity||Grams to Kilograms|
|Boiling Point||672.0±55.0 °C | Condition: Press: 760 Torr|
|Density||1.458±0.06 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr|
|Current Developer||JPH203 was developed by J-Pharma and in clinic phase 1 trials.|
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