JNJ10229570 - CAS 524923-88-4
Catalog number:
524923-88-4
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C22H19N3O2S
Molecular Weight:
389.47
COA:
Inquire
Targets:
Melanocortin (MC) Receptors
Description:
JNJ10229570 is a novel MC1R and MC5R antagonist. It was used to treat primary human sebaceous cells. It might have a potential for the treatment of acne and other sebaceous gland pathologies. It was developed by Johnson & Johnson. It was in phase II clinical trials, but has been terminated.
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Purity:
98%
Appearance:
Solid powder
Synonyms:
JNJ-10229570;2,3-Bis(2-methoxyphenyl)-N-phenyl-1,2,4-thiadiazol-5-imine;Benzenamine, N-(2,3-bis(2-methoxyphenyl)-1,2,4-thiadiazol-5(2H)-ylidene)-
Solubility:
Soluble in DMSO, not in water
Storage:
-20°C Freezer
MSDS:
Inquire
Application:
JNJ10229570 was used to treat primary human sebaceous cells. It might have a potential for the treatment of acne and other sebaceous gland pathologies.
Quality Standard:
In-house standard
Quantity:
Milligrams-Grams
Boiling Point:
541.2±60.0 °C | Condition: Press: 760 Torr
Density:
1.22±0.1 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr
InChIKey:
XTHRTBCPBWJYRO-UHFFFAOYSA-N
InChI:
InChI=1S/C22H19N3O2S/c1-26-19-14-8-6-12-17(19)21-24-22(23-16-10-4-3-5-11-16)28-25(21)18-13-7-9-15-20(18)27-2/h3-15H,1-2H3
Canonical SMILES:
COC1=CC=CC=C1C2=NC(=NC3=CC=CC=C3)SN2C4=CC=CC=C4OC
Current Developer:
JNJ10229570 was developed by Johnson & Johnson. It was in phase II clinical trials, but has been terminated.
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