JNJ-42153605 - CAS 1254977-87-1
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C22H23F3N4
Molecular Weight:
400.44
COA:
Inquire
Targets:
mGluR
Description:
JNJ-42153605 is a selective positive allosteric modulator of the metabotropic glutamate 2 (mGlu2) receptor (EC50= 17 Nm) with an acceptable pharmacokinetic profile in rodent and nonrodent species.
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Brife Description:
A selective positive allosteric modulator of the metabotropic glutamate 2 (mGlu2) receptor (EC50= 17 Nm)
Synonyms:
3-(cyclopropylmethyl)-7-(4-phenylpiperidin-1-yl)-8-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine; 3-cyclopropylmethyl-7-(4-phenylpiperidin-1-yl)-8-trifluoromethyl(1,2,4)triazolo(4,3-a)pyridine; JNJ-42153605
Solubility:
DMSO: 10 mM
Storage:
Store in a cool and dry place (or refer to the Certificate of Analysis).
MSDS:
Inquire
Density:
1.38±0.1 g/cm3
InChIKey:
BQAVZGJJQFJSMW-UHFFFAOYSA-N
InChI:
1S/C22H23F3N4/c23-22(24,25)20-18(10-13-29-19(14-15-6-7-15)26-27-21(20)29)28-11-8-17(9-12-28)16-4-2-1-3-5-16/h1-5,10,13,15,17H,6-9,11-12,14H2
Canonical SMILES:
C1CC1CC2=NN=C3N2C=CC(=C3C(F)(F)F)N4CCC(CC4)C5=CC=CC=C5
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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CAS 1254977-87-1 JNJ-42153605

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