JNJ-42041935 - CAS 1193383-09-3
Catalog number: 1193383-09-3
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C12H6ClF3N4O3
Molecular Weight:
346.65
COA:
Inquire
Targets:
HIF/HIF Prolyl-Hydroxylase
Description:
JNJ-42041935 is a potent (pK(I) = 7.3-7.9), 2-oxoglutarate competitive, reversible, and selective inhibitor of PHD enzymes. JNJ-42041935 is a new pharmacological tool, which can investigate PHD inhibition and demonstrate that PHD inhibitors offer great promise for the treatment of inflammation-induced anemia.
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Purity:
98%
Appearance:
Solid powder
Synonyms:
JNJ-42041935; JNJ 42041935; JNJ42041935.
Solubility:
Soluble in DMSO, not in water
Storage:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
MSDS:
Inquire
Shelf Life:
2 years if stored properly
Canonical SMILES:
ClC1=CC2=C(NC(N3C=C(C(O)=O)C=N3)=N2)C=C1OC(F)(F)F
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