JNJ-41443532 - CAS 1228650-83-6
Catalog number:
1228650-83-6
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C22H25F3N4O3S
Molecular Weight:
482.52
COA:
Inquire
Targets:
CCR
Description:
This active molecular is a CCR2 receptor antagonist which is applicated for the treatment of type-2 diabetes mellitus under the development of Janssen Research & Development. In 2010, Phase-I clinical trials in Type-2 diabetes mellitus was on-going. in Belgium and USA.
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Purity:
98%
Appearance:
Powder
Synonyms:
N-(2-((1-(trans-4-hydroxy-4-(5-thiazolyl)cyclohexyl)-3-azetidinyl)amino)-2-oxoethyl)-3-(trifluoromethyl)Benzamide
Solubility:
Soluble in DMSO
Storage:
-20°C Freezer
MSDS:
Inquire
Application:
type-2 diabetes mellitus
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Milligrams-Grams
InChIKey:
CFKBNYUHQSQBSX-CYWCHRQTSA-N
InChI:
1S/C22H25F3N4O3S/c23-22(24,25)15-3-1-2-14(8-15)20(31)27-10-19(30)28-16-11-29(12-16)17-4-6-21(32,7-5-17)18-9-26-13-33-18/h1-3,8-9,13,16-17,32H,4-7,10-12H2,(H,27,31)(H,28,30)/t17-,21-
Canonical SMILES:
c1cc(cc(c1)C(=O)NCC(=O)NC2CN(C2)[C@H]3CC[C@@](CC3)(O)c4scnc4)C(F)(F)F
Current Developer:
Janssen Research & Development
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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