JNJ-19567470 - CAS 724471-26-5
Catalog number:
724471-26-5
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C22H27BrN4O
Molecular Weight:
443.38
COA:
Inquire
Targets:
Corticotropin-releasing factor (CRF)
Description:
JNJ-19567470 is a selective Corticotropin releasing factor (CRF) receptor antagonist. It is a novel target for developing anti-panic drugs. JNJ-19567470 is as effective as benzodiazepines in treatment of a panic attack which prevents sodium lactate-induced acute panic-like responses. In Oct 2009, preclinical development in Anxiety disorders was ongoing in Japan.
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Purity:
98%
Appearance:
Powder
Synonyms:
TAI-041;R-317573;1-(7-(4-bromo-2,6-dimethylphenyl)-2,5-dimethyl-7H-pyrrolo(2,3-d)pyrimidin-4-yl)-4-Piperidinemethanol
Solubility:
Soluble in DMSO
Storage:
-20℃ Freezer
MSDS:
Inquire
Application:
Anxiety disorders
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Milligrams-Grams
InChIKey:
GGRHUOGLCCJDDN-UHFFFAOYSA-N
InChI:
1S/C22H27BrN4O/c1-13-9-18(23)10-14(2)20(13)27-11-15(3)19-21(24-16(4)25-22(19)27)26-7-5-17(12-28)6-8-26/h9-11,17,28H,5-8,12H2,1-4H3
Canonical SMILES:
Cc1cc(cc(c1n2cc(c3c2nc(nc3N4CCC(CC4)CO)C)C)C)Br
Current Developer:
Originator Janssen L.P.; Taisho Pharmaceutical
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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