JNJ-10329670 - CAS 400797-24-2
Catalog number: 400797-24-2
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C30H34ClF3N6O3S
Molecular Weight:
651.14
COA:
Inquire
Targets:
Others
Description:
JNJ-10329670 represents a novel class of immunosuppressive compounds with a highly potent (Ki ~30 nM)
Purity:
≥98%
Appearance:
Solid powder
Synonyms:
1-(3-(4-(6-chloro-2,3-dihydro-3-methyl-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl)propyl)-4,5,6,7-tetrahydro-5-(methylsulfonyl)-3-(4-(trifluoromethyl)phenyl)-1H-Pyrazolo(4,3-C)pyridine
Solubility:
Soluble in DMSO
Storage:
Store at -20 °C
MSDS:
Inquire
Application:
Immunosuppressant
Quality Standard:
Enterprise standard
Shelf Life:
As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly.
Quantity:
Milligrams-Grams
InChIKey:
NVAHQQYCEWEDKM-UHFFFAOYSA-N
InChI:
1S/C30H34ClF3N6O3S/c1-36-26-9-8-22(31)18-27(26)40(29(36)41)23-10-15-37(16-11-23)13-3-14-39-25-12-17-38(44(2,42)43)19-24(25)28(35-39)20-4-6-21(7-5-20)30(32,33)34/h4-9,18,23H,3,10-17,19H2,1-2H3
Canonical SMILES:
Cn1c2ccc(cc2n(c1=O)C3CCN(CC3)CCCn4c5c(c(n4)c6ccc(cc6)C(F)(F)F)CN(CC5)S(=O)(=O)C)Cl
Current Developer:
Johnson & Johnson
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Products


CAS 37517-30-9 Acebutolol

Acebutolol
(CAS: 37517-30-9)

Acebutolol is a synthetic butyranilide derivative with hypotensive and antiarrhythmic activity as a beta blocker for the treatment of hypertension and arrhythmi...

CAS 153777-70-9 DOTA derivative

DOTA derivative
(CAS: 153777-70-9)

DOTA derivative is a benxyl derivative of the cyclic tosamide; can be nitrated directly; is more convenient to incorporate the nitro group after deprotection li...

CAS 736992-21-5 Elamipretide

Elamipretide
(CAS: 736992-21-5)

Elamipretide is a cardiolipin peroxidase inhibitor and mitochondria-targeting peptide under the development of Stealth BioTherapeutics. It can Improve left Vent...

CAS 1527513-89-8 D9

D9
(CAS: 1527513-89-8)

D9 is a thioredoxin reductase (TrxR) inhibitor (EC50 = 2.8 nM, IC50 = 0.03 and 0.1 μM in MCF-7 cells and HT-29 cells, respectively). It exhibits an inhibitory e...

CAS 72-69-5 nortriptyline

nortriptyline
(CAS: 72-69-5)

Nortriptyline is a second-generation antidepressant originated by Lilly. It is a non-selective monoamine reuptake inhibitor. Nortriptyline can be used for the t...

GI 181771
(CAS: 305366-98-7)

GI-181771X is a novel effect of oral CCK-1 agonist on fasting and postprandial gastric functions in healthy volunteers.

CAS 136849-88-2 Macranthoidin B

Macranthoidin B
(CAS: 136849-88-2)

Macranthoidin B, a triterpenoid saponin compound, could be isolated from flowerbuds of Lonicera and has been found to have potential effect against inflammation...

CAS 509-20-6 Aconine

Aconine
(CAS: 509-20-6)

Aconine is extracted form the roots of Aconitum kusnezoffii Reichb, a derivative of Aconitine.

CAS 101387-97-7 Ro18-5362

Ro18-5362
(CAS: 101387-97-7)

Ro18-5362 is the less active prodrug of Ro 18-5364 which is an extremely potent and rapid inhibitor of the gastric mucosal (H+ + K+)-ATPase.

CAS 882-09-7 Clofibric Acid

Clofibric Acid
(CAS: 882-09-7)

Clofibric acid is a PPAR agonist.

FR-168888
(CAS: 168620-46-0)

FR-168888, a guanidine compound, has been found to be a sodium hydrogen antiporter inhibitor that was once studied in myocardial ischaemia therapy.

BPTES
(CAS: 314045-39-1)

BPTES is a potent and selective Glutaminase GLS1 (KGA) inhibitor with IC50 of 0.16 μM.

CAS 599151-35-6 FQI 1

FQI 1
(CAS: 599151-35-6)

FQI 1 is a cell-permeable and reversible inhibitor of α-globin transcription factor CP2 (LSF; IC50 = 2.1 μM) and an antiproliferative. FQI 1 induces apoptosis i...

CAS 52286-59-6 Ginsenoside Re

Ginsenoside Re
(CAS: 52286-59-6)

Ginsenoside Re, extracted from the traditional Chinese herb ginseng, responsible for some of the pharmacological functions.

CAS 93987-29-2 BI 6015

BI 6015
(CAS: 93987-29-2)

BI 6015 is a hepatocyte nuclear factor 4α (HNF4α) antagonist that suppresses expression of known HNF4α target genes. BI 6015 produces cytotoxicity in a range of...

CAS 7013-41-4 Talopram hydrochloride

Talopram hydrochloride
(CAS: 7013-41-4)

Talopram hydrochloride is a potent and selective inhibitor of the noradrenalin transporter (NET) (IC50 = 2.9 nM) that has selectivity for NET against SERT (5-HT...

CAS 1786-81-8 Prilocaine hydrochloride

Prilocaine hydrochloride
(CAS: 1786-81-8)

Prilocaine hydrochloride is a local anesthetic of the amino amide type.

CAS 290821-39-5 Cimiracemoside D

Cimiracemoside D
(CAS: 290821-39-5)

Cimiracemoside D is a natural product found in Actaea racemosa with unknown details.

CAS 109-57-9 Allylthiourea

Allylthiourea
(CAS: 109-57-9)

Allylthiourea is a metabolic inhibitor that selective inhibits ammonia oxidation.

CAS 863987-12-6 ZIP

ZIP
(CAS: 863987-12-6)

ZIP is a cell-permeable inhibitor of protein kinase Mζ (PKMζ), which is a constitutively active and atypical PKC isozyme involved in LTP maintenance. ZIP select...

Quick Inquiry

Verification code

Featured Items