JNJ-10329670 - CAS 400797-24-2
Catalog number: 400797-24-2
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C30H34ClF3N6O3S
Molecular Weight:
651.14
COA:
Inquire
Targets:
Others
Description:
JNJ-10329670 represents a novel class of immunosuppressive compounds with a highly potent (Ki ~30 nM)
Publictions citing BOC Sciences Products
  • >> More
Purity:
≥98%
Appearance:
Solid powder
Synonyms:
1-(3-(4-(6-chloro-2,3-dihydro-3-methyl-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl)propyl)-4,5,6,7-tetrahydro-5-(methylsulfonyl)-3-(4-(trifluoromethyl)phenyl)-1H-Pyrazolo(4,3-C)pyridine
Solubility:
Soluble in DMSO
Storage:
Store at -20 °C
MSDS:
Inquire
Application:
Immunosuppressant
Quality Standard:
Enterprise standard
Shelf Life:
As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly.
Quantity:
Milligrams-Grams
InChIKey:
NVAHQQYCEWEDKM-UHFFFAOYSA-N
InChI:
1S/C30H34ClF3N6O3S/c1-36-26-9-8-22(31)18-27(26)40(29(36)41)23-10-15-37(16-11-23)13-3-14-39-25-12-17-38(44(2,42)43)19-24(25)28(35-39)20-4-6-21(7-5-20)30(32,33)34/h4-9,18,23H,3,10-17,19H2,1-2H3
Canonical SMILES:
Cn1c2ccc(cc2n(c1=O)C3CCN(CC3)CCCn4c5c(c(n4)c6ccc(cc6)C(F)(F)F)CN(CC5)S(=O)(=O)C)Cl
Current Developer:
Johnson & Johnson
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Products


CAS 719277-30-2 ProINDY

ProINDY
(CAS: 719277-30-2)

ProINDY, the prodrug form of INDY, is a cell permeable ATP-competitive DYRK1A/B inhibitor.

CAS 17625-83-1 4'-Aminobenzanilide

4'-Aminobenzanilide
(CAS: 17625-83-1)

4’-Aminobenzanilide, a significant intermediate, could be widely used in the formation of drugs, dyestuff and agrochemicals.

CAS 135701-69-8 N-Acetylglycyl-D-glutamic acid

N-Acetylglycyl-D-glutamic acid
(CAS: 135701-69-8)

N-Acetylglycyl-D-glutamic acid is a kind of excitatory peptide. It is more potent than L-glutamic acid at inducing seizures in mice.

DPY-2103
(CAS: 4792-10-3)

DPY-2103 is a useful intermediate for chemical synthesis of a number of biologically active drugs.

CAS 4673-26-1 Diphenyleneiodonium chloride

Diphenyleneiodonium chloride
(CAS: 4673-26-1)

Diphenyleneiodonium chloride has been found to be a GPR3 agonist and also exhibit inhibition against NO synthase, NADG reductase and NADPH oxidase.

MIR96-IN-1
(CAS: 1311982-88-3)

MIR96-IN-1, a benzimidazole derivative, could restrain microRNA-96 biogenesis and also be probable to lead to the apoptosis of cancer cells.

CAS 223666-07-7 Collagen proline hydroxylase inhibitor

Collagen proline hydroxylase inhibitor
(CAS: 223666-07-7)

Collagen proline hydroxylase inhibitor is a collagen proline hydroxylase inhibitor; useful for antifibroproliferative agents.

Integrin Antagonist 1 hydrochloride
(CAS: 1629249-40-6)

Integrin Antagonist 1 hydrochloride, a naphthyridine derivative, is a small molecule antagonist of integrin αvβ6. In the Fluorescence Polarisation Assay: human ...

CAS 537-12-2 Diperodon hydrochloride

Diperodon hydrochloride
(CAS: 537-12-2)

Diperodon hydrochloride is a local anaesthetics designated by chemical abstracts as 3-piperidino-1,2-propanediol dicarbanilate monohydrate.

MK 1-907
(CAS: 78150-06-8)

MK-1-907 is a centrally acting drug, but no detailed information has been published yet.

CAS 1207258-55-6 NVS-CRF38

NVS-CRF38
(CAS: 1207258-55-6)

NVS-CRF38 is a novel corticotropin-releasing factor receptor 1 (CRF1) antagonist with low water solubility.

Burosumab
(CAS: 1610833-03-8)

Burosumab is a human monoclonal antibody targeting the phosphaturic hormone fibroblast growth factor 23 (FGF23). Burosumab is currently in a phase III clinical ...

CAS 222030-63-9 Fosbretabulin

Fosbretabulin
(CAS: 222030-63-9)

Fosbretabulin, also called as CA4P, has antitumor activity against anaplastic thyroid cancer (ATC) cell lines. Fosbretabulin, a novel water-soluble vascular-dis...

CAS 41498-37-7 GS 389

GS 389
(CAS: 41498-37-7)

GS 389 is a novel tetrahydroisoquinoline analog which significantly increased cGMP levels in the rat aorta and inhibited cGMP phosphodiesterase from the rabbit ...

FR 121196
(CAS: 133920-65-7)

FR 121196 is a potential antidementia drug originated by Fujisawa. Mechanism of Action is not undefined. FR 121196 can ameliorate the impaired memory of rat in ...

Afoxolaner
(CAS: 1093861-60-9)

Afoxolaner is a potent isoxazoline insecticide and acaricide against Ixodes scapularis in dogs. It is indicated for the treatment and prevention of flea infesta...

CAS 4884-68-8 Hydrastinine hydrochloride

Hydrastinine hydrochloride
(CAS: 4884-68-8)

Hydrastinine hydrochloride is a semisynthetic alkaloid as a haemostatic drug.

ATR-101 HCl
(CAS: 133825-81-7)

ATR-101 is a selective Acetyl CoA C-acetyltransferase inhibitor. ATR-101 is uniquely distributed to adrenal tissues and inhibition of adrenal ACAT1 by ATR-101 d...

CAS 16320-04-0 Gestrinone

Gestrinone
(CAS: 16320-04-0)

Gestrinone, also called as R2323, is a synthetic steroid hormone occasionally used to treat endometriosis and it inhibits leiomyoma cells (IC50= 43.67 μM).

CAS 131-53-3 Dioxybenzone

Dioxybenzone
(CAS: 131-53-3)

Dioxybenzone, a phenol derivative, could be widely used to block UVB and UVA in sunscreen products.

Quick Inquiry

Verification code

Featured Items