Ixazomib citrate - CAS 1239908-20-3
Catalog number:
1239908-20-3
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C20H23BCl2N2O9
Molecular Weight:
517.12
COA:
Inquire
Targets:
Proteasome
Description:
The citrate salt form of Ixazomib which is a proteasome inhibitor. It is considered a rollover Phase II trial against multiple myeloma, amyloidosis and lymphoma in sorts of countries. IC50: 3.4 nM.
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Purity:
98%
Related CAS:
1201902-80-8; 1072833-77-2 (free base)
Appearance:
White to off-white solid powder
Synonyms:
4-(carboxymethyl)-2-((R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutyl)-6-oxo-1,3,2-dioxaborinane-4-carboxylic acid; MLN9708; MLN-9708; MLN 9708; ixazomib citrate MMLN-2238-prodrug Ixazomib-prodrug; Ninlaro
Solubility:
DMSO 103 mg/mL; Water <1 mg/mL
Storage:
-20ºC Freeze
MSDS:
Inquire
Application:
HDAC-IN-1, an analogue of MC 1568, is a Iia HDACs inhibitor that could probably influence myogenesis and adipogenesis.
Shelf Life:
As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly
Quantity:
Milligrams-Grams
InChIKey:
YTXSYWAKVMZICI-PVCZSOGJSA-N
InChI:
1S/C20H23BCl2N2O9/c1-10(2)5-14(21-33-17(29)8-20(34-21,19(31)32)7-16(27)28)25-15(26)9-24-18(30)12-6-11(22)3-4-13(12)23/h3-4,6,10,14H,5,7-9H2,1-2H3,(H,24,30)(H,25,26)(H,27,28)(H,31,32)/t14-,20?/m0/s1
Canonical SMILES:
O=C(C(C1)(CC(O)=O)OB([C@@H](NC(CNC(C2=CC(Cl)=CC=C2Cl)=O)=O)CC(C)C)OC1=O)O
Current Developer:
Millennium Pharmaceuticals
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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