|B0084-272158||50 mg||$198||In stock|
IWP 4 is a novel and potent inhibitor of Wnt/β-catenin signaling with IC50 value of 25 nM. It blocks palmitylation, subsquent secretion and activity of Wnt. It ...
IWP-L6 is a highly potent Porcn inhibitor with EC50 of 0.5 nM.
IWP 12 is a Wnt inhibitor that prevents palmitylation of Wnt proteins by Porcupine (Porcn). It blocks post resection juvenile zebrafish tailfin regeneration and...
LGK974 is a selective and orally bioavailable Porcupine inhibitor under development for the treatment of cancers that are driven by the Wnt pathway in a Wnt lig...
Wnt-C59 is a very potent and highly selective Wnt signaling antagonist with an IC50 ~ 74 pM in the Wnt signaling reporter assay.
GNF1331 is a potent, selective and orally bioavailable porcupine (PORCN) inhibitor with IC50 value of 12 nM. It plays a critical role in multiple cancers, such ...