Ivosidenib - CAS 1448347-49-6
Catalog number:
1448347-49-6
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C28H22ClF3N6O3
Molecular Weight:
582.96
COA:
Inquire
Targets:
Isocitrate Dehydrogenase (IDH)
Description:
Ivosidenib, also called AG-120, is an oral inhibitor that specifically inhibits a mutated form of IDH1 in the cytoplasm.
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Related CAS:
1448346-63-1 (AG-120 racemic)
Appearance:
Solid powder
Synonyms:
(S)-N-((S)-1-(2-chlorophenyl)-2-((3,3-difluorocyclobutyl)amino)-2-oxoethyl)-1-(4-cyanopyridin-2-yl)-N-(5-fluoropyridin-3-yl)-5-oxopyrrolidine-2-carboxamide; Ivosidenib, AG-120; AG120; AG 120; RG-120; RG 120; RG120
Solubility:
Soluble in DMSO
Storage:
Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -65℃ for long term (months to years).
MSDS:
Inquire
Shelf Life:
2 years
Quantity:
Grams-Kilos
Boiling Point:
854.3±65.0 °C | Condition: Press: 760 Torr
Density:
1.51±0.1 g/cm3
InChIKey:
WIJZXSAJMHAVGX-DHLKQENFSA-N
InChI:
1S/C28H22ClF3N6O3/c29-21-4-2-1-3-20(21)25(26(40)36-18-11-28(31,32)12-18)37(19-10-17(30)14-34-15-19)27(41)22-5-6-24(39)38(22)23-9-16(13-33)7-8-35-23/h1-4,7-10,14-15,18,22,25H,5-6,11-12H2,(H,36,40)/t22-,25-/m0/s1
Canonical SMILES:
O=C([C@H](CC1)N(C2=NC=CC(C#N)=C2)C1=O)N([C@@H](C3=CC=CC=C3Cl)C(NC4CC(F)(F)C4)=O)C5=CC(F)=CN=C5
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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