Isovitexin - CAS 29702-25-8
Catalog number: 29702-25-8
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C21H20O10
COA:
Inquire
Chemical Family:
Flavonoids
Publictions citing BOC Sciences Products
  • >> More
Purity:
>98%
Appearance:
Powder
MSDS:
Inquire
Quality Standard:
Enterprise Standard
Quantity:
Milligrams-Grams
1.Molecular targets of vitexin and isovitexin in cancer therapy: a critical review.
Ganesan K;Xu B Ann N Y Acad Sci. 2017 Aug;1401(1):102-113. doi: 10.1111/nyas.13446.
Cancer is a primary public health problem and the second leading cause of death worldwide. It causes life-threatening malignancies and results in high financial costs for both patients and the healthcare system. Hence, it is important to develop effective long-term strategies pertaining to prevention and control of cancers. Plant-derived secondary metabolites have been shown to have positive roles against various cancers. A number of plant extracts have been evaluated for possible use in the treatment of cancer; some have provided direction for new strategies for the research and development of antitumor agents. Here, we provide comprehensive data on various cancers, potential molecular mechanisms, and therapeutic implications of just two plant-derived compounds, vitexin and isovitexin. Information on the chemotherapeutic potential of vitexin and isovitexin was collected from a library database and through electronic searches (ScienceDirect, Pubmed, and Google Scholar).
2.[Chemical Components from Leaves of Fatsia japonica and Their Antitumor Activities in vitro].
Wei Q;Qiu Z;Xu F;Li QR;Yin H Zhong Yao Cai. 2015 Apr;38(4):745-50.
OBJECTIVE: ;To study the chemical components from the leaves of Fatsia japonica and their antitumor activities in vitro.;METHODS: ;All compounds were separated and purified by column chromatography over silica gel, Sephadex LH-20 and preparative HPLC. Their structures were identified by physical and chemical properties and spectral methods including 1H-NMR and 13C-NMR. Antitumor assay was measured by MTT method.;RESULTS: ;18 compounds were isolated and identified as palmitic acid (1), β-hydroxypropiovanillone (2), adenosine (3), β-sitosterol (4), daucosterol (5), oleanolic acid (6), echinocystic acid (7), betulinic acid (8), hederagenin(9), hederagenin-3-O-α-L-rhamnopyranosyl(1-->2)-α-L-arabinopyranoside(10), acacetin(11), quercetin(12), quercetin-3-O-β-D-glucopyranoside(13), isovitexin(14), isovitexin-7-O-glucoside(15), astragalin(16), methylpluviatolide(17), and syringaresinol-4-O-β-D-glucopyranoside(18).;CONCLUSION: ;All compounds are isolated from the leaves of Fatsia japonica for the first time except compound 1.
3.Effects of C-glycosylation on anti-diabetic, anti-Alzheimer's disease and anti-inflammatory potential of apigenin.
Choi JS;Islam MN;Ali MY;Kim EJ;Kim YM;Jung HA Food Chem Toxicol. 2014 Feb;64:27-33. doi: 10.1016/j.fct.2013.11.020. Epub 2013 Nov 27.
Apigenin has gained particular interests in recent years as a beneficial and health promoting agent because of its low intrinsic toxicity. Vitexin and isovitexin, naturally occurring C-glycosylated derivatives of apigenin, have been known to possess potent anti-diabetic, anti-Alzheimer's disease (anti-AD), and anti-inflammatory activities. The present study was designed to investigate the anti-diabetic, anti-AD, and anti-inflammatory potential of apigenin and its two C-glycosylated derivatives, vitexin and isovitexin by in vitro assays including rat lens aldose reductase (RLAR), human recombinant aldose reductase (HRAR), advanced glycation endproducts (AGEs), protein tyrosine phosphatase 1B (PTP1B), acetylcholinesterase (AChE), butyrylcholinesterase (BChE), β-site amyloid precursor (APP) cleaving enzyme 1 (BACE1), and nitric oxide (NO), inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) in lipopolysaccharide (LPS)-induced RAW 264.
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Flavonoids Products


CAS 76754-24-0 Lupalbigenin

Lupalbigenin
(CAS: 76754-24-0)

Lupalbigenin isolated from the roots of Glycyrrhiza uralensis Fisch. It sensitizes detachment-induced cell death in human lung cancer cell through down-regulati...

CAS 20310-89-8 Saponarin

Saponarin
(CAS: 20310-89-8)

Saponarin is a compound of the flavonoid class found in the seeds of Vaccaria segetalis. Saponarin exhibits antioxidant and anti-inflammatory properties.

CAS 15486-33-6 3,5-Dihydroxy-4',7-dimethoxyflavone

3,5-Dihydroxy-4',7-dimethoxyflavone
(CAS: 15486-33-6)

3,5-Dihydroxy-4',7-dimethoxyflavone is a natural flavonoid found in the herb of Andrographis paniculata (Burm. f.) Nees.

CAS 29838-67-3 Astilbin

Astilbin
(CAS: 29838-67-3)

Astilbin isolated from the rhizomes of Astilbe chinensis (Maxim.) Franch. et Sav. It could be a candidate drug for inflammatory bowel disease by mediating the r...

CAS 97938-31-3 Leachianone A

Leachianone A
(CAS: 97938-31-3)

Leachianone A isolated from the roots of Sophora flavescens. And it possesses a profound cytotoxic activity against human hepatoma cell line HepG2 in vitro.

CAS 522-17-8 Deguelin

Deguelin
(CAS: 522-17-8)

Deguelin is a flavonoid compound found in the herbs of Derris robusta. By targeting Akt in dual axis, deguelin possesses antitumor effection. Deguelin also show...

CAS 51938-32-0 Schaftoside

Schaftoside
(CAS: 51938-32-0)

Antioxidant; Anticancer

CAS 520-27-4 Diosmin

Diosmin
(CAS: 520-27-4)

Diosimin, that can be isolated from the herbs of Scrophularia nodosa, has shown beneficial effect in preventing the progression of early diabetic neuropathy in ...

Dodoviscin A
(CAS: 1372527-25-7)

Dodoviscin A is a flavonoid compound found in the herbs of Dodonaea viscosa. The compound may be a new promising pigmentation-altering agent for cosmetic and th...

Epimedokoreanin B
(CAS: 161068-53-7)

Epimedokoreanin B isolated from the herbs of Epimedium brevicornum.

CAS 29702-25-8 Isovitexin

Isovitexin
(CAS: 29702-25-8)

CAS 62949-79-5 Mulberrin

Mulberrin
(CAS: 62949-79-5)

Mulberrin isolated from the root bark of Morus alba L. It may as HIV-1 reverse transcriptase inhibitor.

CAS 14259-46-2 Narirutin

Narirutin
(CAS: 14259-46-2)

Anti-inflammatory. The flavonoid narirutin could reduce airway inflammation in ovalbumin (OVA)-sensitized / challenged NC / Nga mice, a model of allergic eosino...

CAS 94942-49-1 6-Methoxynaringenin

6-Methoxynaringenin
(CAS: 94942-49-1)

6-Methoxynaringenin isolated from the herbs of Humulus lupulus.

Sophoflavescenol
(CAS: 216450-65-6)

Sophoflavescenol is a compound of the flavonoid class found in the roots of Sophora flavescens Ait. Sophoflavescenol is a PDE5 inhibitor with antioxidant and an...

CAS 20725-03-5 Fustin

Fustin
(CAS: 20725-03-5)

Fustin is a natural compound isolated from the peel of Toxicodendron vernicifluum F. Barkley. Fustin shows protective effects on 6-hydroxydopamine-induced neuro...

CAS 140147-77-9 Epimedin A1

Epimedin A1
(CAS: 140147-77-9)

Anti-osteoporosis.

CAS 104055-79-0 Dihydroobovatin

Dihydroobovatin
(CAS: 104055-79-0)

Dihydroobovatin isolated from the herbs of Erythrina indica.

Sanggenol L
(CAS: 329319-20-2)

Sanggenol L is a pyranoflavanone found in the root bark of Morus alba L. Study shows that Sanggenol L has the therapeutic effect on ovarian cancer.

CAS 70897-14-2 Dihydrocitflavanone

Dihydrocitflavanone
(CAS: 70897-14-2)

Chemical Structure

CAS 29702-25-8 Isovitexin

Quick Inquiry

Verification code

Featured Items