|Description||A tetracyclic diterpenoid with a beyerane core has drawn attention because it can exhibit antihypertensive activity, reduce blood glucose, suppress cancer cells.|
Ancriviroc, an oximino-piperidino-piperidine-amide, is a CCR5 receptor antagonist.
HQL 79 is a selective inhibitor of human hematopoietic prostaglandin D synthase (H-PGDS) (IC50 = 6 μM). HQL 79 is potentially used as an antihistamine that exer...
BIX NHE1 inhibitor
BIX NHE1 inhibitor is a potent and selective NHE1 inhibitor (IC50 = 31 nM). It attenuates ischemic damage in an ischemia reperfusion injury isolated rat heart m...
4-Azido-L-phenylalanine is an unnatural derivative of L-phenylalanine, a nonpolar, essential amino acid that naturally occurs in the human body and is also used...
BML 111 is a FPR2 (lipoxin A4 receptor) agonist. It inhibits tumor-related angiogenesis and reduces tumor growth in hepatoma H22 cell bearing mice. BML 111 also...
UAMC00039 dihydrochloride is a potent, reversible and competitive dipeptidyl peptidase II inhibitor (IC50= 0.48 nM) with selectivity against DPP-9, DPP-8 and DP...
Blasticidin S HCl
Blasticidin S HCl is a nucleoside antibiotic that is first isolated from Streptomyces griseochromogenes. Blasticidin S inhibits protein synthesis in both prokar...
Erythritol tetranitrate is an explosive compound. It is also a vasodilator, and was the active ingredient in the original "sustained release" tablets, made unde...
BAY-876 is a potent and selective GLUT1 inhibitor (IC50 = 2 nM) with good stability in vitro and high bioavailability in vivo. BAY-876 can be used as an antican...
Ginsenoside Ro, the predominant ginsenoside in the rhizome, shows no hemolytic nor cytotoxic activities.
YMU1 is a human thymidylate kinase (hTMPK; IC50 value 1.65 µM) inhibitor yet not has inhibitory effect on the activity of purified thymidine kinase 1 (TK1). YMU...
AAI101 is a novel β-lactamase inhibitor with activity against extended-spectrum β-lactamases (ESBL), as well as, some class A and class D carbapenemases.
9-Aminoacridine is a highly fluorescent dye, an acridine analog. It is used clinically as a topical antiseptic and experimentally as a mutagen. It is an intrace...
BPH-652, also known as BMS-187745, has been found to be a SQS inhibitor that could probably be effective against S. aureus infections.
Diacerin is an inhibitor of pro-inflammatory cytokine Interleukin-1B (IL-1B) production, prescribed for osteoarthritis and chronic inflammatory arthritis.
DL-α-Lipoic acid is an non-specific free radical scavenger and has anti-oxidant properties. It could be used as a fat-metabolism stimulator.
GSK-114 is a potent and selective TNNI3K inhibitor (TNNI3 IC50 = 25nM; B-RafV600E IC50 = 1000 nM). GSK-114 displays significant bias (40-fold) for TNNI3K over B...
Limaprost is a potent platelet adhesion inhibitor and vasodilator that increases blood flow and inhibits platelet aggregation. It is an analog of prostaglandin ...
This active molecular is 3-amidinophenylalanine-derived prodrug targeting the human urokinase plasminogen activator (uPA) system. It is a second generation seri...
Meptyldinocap (2,4-DNOPC) is a novel powdery mildew (Erysiphe necator) fungicide which shows protectant and post-infective activities.