|Description||ISO-1 is an inhibitor of the dopachrome tautomerase activity of MIF. It blocks the activation of NF-κB and TNF-α secretion from LPS-treated macrophages and improves the survival of mice following sepsis.It also demonstrates protective effects in airway and gastrointestinal inflammation in mice.|
Poliumoside is a natural compound extracted from Beautyberry extract, which exhibit significant inhibition of advanced glycation end product formation. It exhib...
Disufenton, a benzenesulfonate compound, has been found to be a free radical scavenger that was once studied in acute ischaemic stroke therapy as a neuroprotect...
BMS-214662 mesylate is a potent and selective inhibitor of farnesyltransferase that induces mitochondrial apoptosis in chronic myeloid leukemia stem/progenitor ...
Caftaric acid is a natural productwhich was reported as an inhibitor of the protein-protein interactions mediated by the Src-family kinases.
Alendronate sodium hydrate
Alendronate, a nitrogen-containing bisphosphonate, is a potent inhibitor of bone resorption used for the treatment and prevention of osteoporosis.
Kauniolide is a natural compound.
Remeglurant is a selective Metabotropic glutamate receptor 5 antagonist originated by Merz Pharmaceuticals. Phase-I for Drug-induced dyskinesia in USA was on-go...
SPDP is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide...
Cefpirome Sulfate is a fourth generation cephalosporin antibiotic. It was developed by German company Hoechst and France Roussel company together.
Tetrabenazine is a VMAT-inhibitor used for treatment of hyperkinetic movement disorder. It is a monoamine-depleting and a dopamine-receptor-blocking drug and is...
Dirlotapide is a drug used to treat obesity in dogs works as a gut-selective microsomal triglyceride transfer protein (MTTP or MTP) inhibitor.
Aspartic acid calcium
Aspartic acid calcium is a chelate where calcium is attached to L-Aspartic acid, an amino acid that is used in the biosynthesis of proteins
Cefacetrile, a derivative of 7-aminocephalosporanic acid, is a broad-spectrum first generation cephalosporin with antibiotic and antibacterial activity. It is e...
Aminocaproic acid is a derivative and analogue of the amino acid lysine, which makes it an effective inhibitor for enzymes that bind that particular residue. Su...
Azathioprine is an immunosuppressive drug, inhibiting purine synthesis and GTP-binding protein Rac1 activation, used in the treatment of organ transplantation a...
Glybuzole, a benzenesulfonamide derivative, has been found to have antihyperglycemic through stimulating the release of insulin.
1,8-Dihydroxyanthraquinone, an anthraquinone derivative, could be widely used as antioxidant, dye intermediate and a raw material to synthesise sorts of product...
Isochlorogenic acid C
Source from The herbs of Laggera alata, Isochlorogenic acid C is a selective inhibitor of human immunodeficiency virus type 1 integrase.
Chlorambucil (marketed as Leukeran by GlaxoSmithKline) is a chemotherapy drug that has been mainly used in the treatment of chronic lymphocytic leukemia. It is ...
Hydralazine HCl is a hydrochloride salt of hydralazine (Apresoline) that is a direct-acting smooth muscle relaxant with an IC50 of 1.9 mM.