|Description||Ipragliflozin is a highly potent and selective SGLT2 inhibitor and has little and NO potency for SGLT1/3/4/5/6.|
Ipragliflozin is a highly potent and selective SGLT2 inhibitor and has little and NO potency for SGLT1/3/4/5/6.
Canagliflozin hemihydrate is a highly potent and selective inhibitor of subtype 2 sodium-glucose transport protein (SGLT2), which is responsible for at least 90...
hloretin is a dihydrochalcone, a type of natural phenols, which shows beneficial effects on diabetes.
PF-04971729, a potent and selective inhibitor of the sodium-dependent glucose cotransporter 2, is currently in phase 2 trials for the treatment of diabetes mell...
Phlorizin is a 2'-glucoside of phloretin. It belongs to the group of dihydrochalcones, a type of flavonoids.
Atigliflozin is a selective sodium-glucose co-transporter subtype 2 (SGLT2) inhibitor. It has antihyperglycemic activity and is used as an antihyperglycaemic dr...
EGT1442 is a potent and selective SGLT2 inhibitor with IC50 value of 5.6 μM /2 nM in SGLT1 /SGLT2 respectively. It significantly prolonged the median survival o...
Mizagliflozin is a sodium-glucose transporter inhibitor. It is expected to improve postprandial hyperglycemia by suppressing glucose absorption from the intesti...
Remogliflozin is a selective inhibitor of sodium-glucose transporter 2 (SGLT2) that promotes blood glucose to be eliminated through the urine. The prodrug Remog...
LIK066 is a potent Sodium-glucose transporter 1 and Sodium-glucose transporter 2 inhibitor originated by Novartis Pharmaceuticals Corporation IC50 value is 22.0...
TA-1887 is a selective Sodium Glucose Cotransporter 2 Inhibitor with pronounced antihyperglycemic effects in high-fat diet-fed KK (HF-KK) mice. It may be used f...
Canagliflozin is a sodium/glucose cotransporter 2 (SGLT2) inhibitor. Canagliflozin has been shown to dose dependently reduce calculated renal threshold for gluc...
Dapagliflozin (2S)-1,2-propanediol, hydr
Dapagliflozin (2S)-1,2-propanediol, hydrate is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2). It is in developm...
Tofogliflozin(CSG-452) hydrate is a potent and highly specific sodium/glucose cotransporter 2(SGLT2) inhibitor with Ki values of 2.9, 14.9, and 6.4 nM for human...
KGA2727 is a selective and potent SGLT1 inhibitor for the treatment of diabete. Its inhibition constant (Ki) values of 97 and 13,600 nM for human (h) SGLT1 and ...
Empagliflozin is a potent and selective SGLT-2 inhibitor with IC50 of 3.1 nM, exhibits >300-fold selectivity over SGLT-1, 4, 5 and 6.
Tofogliflozin is an experimental drug for the treatment of diabetes mellitus and is being developed by Chugai Pharma in collaboration with Kowa and Sanofi. It i...
LX-4211 is a potent dual SGLT2/1 inhibitor; Antidiabetic agents.
Dapagliflozin(BMS512148) is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) is in development for the treatment o...