IP7e - CAS 500164-74-9
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
C23H22N2O4
Molecular Weight:
390.43
COA:
Inquire
Targets:
Others
Description:
IP7e is a potent Nurr1 (NR4A2) activator with EC50 value of 3.9 nM, which is important in the development and maintenance of midbrain dopaminergic neurons and is independent of endogenous activation. It suppresses NF-κB signaling. It reduces severity of symptoms in mice with experimental autoimmune encephalomyelitis (EAE). It is brain penetrant and orally bioavailable.
Purity:
≥98% by HPLC
Synonyms:
IP7e; IP 7e; IP-7e; isoxazolo-pyridinone 7e; 6-[4-[(2-Methoxyethoxy)methyl]phenyl]-5-methyl-3-phenyl-isoxazolo[4,5-c]pyridin-4(5H)-one
MSDS:
Inquire
InChIKey:
YCAACZFPADQMAR-UHFFFAOYSA-N
InChI:
InChI=1S/C23H22N2O4/c1-25-19(17-10-8-16(9-11-17)15-28-13-12-27-2)14-20-21(23(25)26)22(24-29-20)18-6-4-3-5-7-18/h3-11,14H,12-13,15H2,1-2H3
Canonical SMILES:
CN1C(=CC2=C(C1=O)C(=NO2)C3=CC=CC=C3)C4=CC=C(C=C4)COCCOC
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Products


CAS 443776-49-6 BC 11 hydrobromide

BC 11 hydrobromide
(CAS: 443776-49-6)

BC 11 hydrobromide is a selective urokinase (uPA) inhibitor (IC50 = 8.2 μM) with no activity at 8 other related enzymes. BC 11 inhibits clot lysis displaying no...

CAS 129909-90-6 Amicarbazone

Amicarbazone
(CAS: 129909-90-6)

The phenotypic responses of sensitive plants exposed to amicarbazone include chlorosis, stunted growth, tissue necrosis, and death. Its efficacy as both a folia...

Fosravuconazole
(CAS: 351227-64-0)

Fosravuconazole is an azole antifungal agent potentially for the treatment of fungal infections, as a water-soluble prodrug of ravuconazole that is being develo...

CAS 290821-39-5 Cimiracemoside D

Cimiracemoside D
(CAS: 290821-39-5)

Cimiracemoside D is a natural product found in Actaea racemosa with unknown details.

CAS 70788-28-2 Flurofamide

Flurofamide
(CAS: 70788-28-2)

Flurofamide is a bacterial urease inhibitor used for the treatment of gastritis and irregular urease activity in the urinary tract.

Canfosfamide Hydrochloride
(CAS: 439943-59-6)

Canfosfamide is a modified glutathione analogue as a small-molecule antineoplastic compound with potential antineoplastic activity. Canfosfamide is selectively ...

CAS 218795-74-5 IMM 01

IMM 01
(CAS: 218795-74-5)

IMM 01 is an agonist of mammalian Diaphanous (mDia)-related formins that inhibits DID–DAD binding (IC50 value 140 nM).

RUSKI-201 dihydrochloride

RUSKI-201 dihydrochloride is a sonic hedgehog acyltransferase (HHAT) inhibitor (IC50 = 0.20 μM) devoid of off-target cytotoxicity, and quantitative whole-proteo...

Chemical Structure

CAS 500164-74-9 IP7e

Quick Inquiry

Verification code

Featured Items