Iobenguane - CAS 77679-27-7
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Not Intended for Therapeutic Use. For research use only.
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I 131 Metaiodobenzylguanidine. Iodine I 131 Metaiodobenzylguanidine. 131 I-MIBG.
1.Role of (123)I-Iobenguane Myocardial Scintigraphy in Predicting Short-term Left Ventricular Functional Recovery: An Interesting Image.
Feola M1, Chauvie S2, Biggi A2, Testa M1. J Clin Imaging Sci. 2015 Oct 30;5:56. doi: 10.4103/2156-7514.168707. eCollection 2015.
(123)I-iobenguane myocardial scintigraphy (MIBG) has been shown to be a predictor of sudden cardiac mortality in patients with heart failure. One patient with recent anterior myocardial infarction (MI) treated with coronary angioplasty and having left ventricular ejection fraction (LVEF) of 30% underwent early MIBG myocardial scintigraphy/tetrofosmin single-photon emission computed tomography (SPECT) in order to help evaluate his eligibility for implantable cardioverter defibrillator (ICD). The late heart/mediastinum (H/M) ratio was calculated to be 1.32% and the washout rate was 1%. At 40-day follow-up after angioplasty, LVEF proved to be 32%, New York Heart Association (NYHA) class was still II-III, and an ICD was placed in order to reduce mortality from ventricular arrhythmias. MIBG myocardial scintigraphy might be a promising method for evaluating left ventricular recovery in post-MI patients.
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