|Description||inS3-54A18 is a potent inhibitor of the DNA-binding domain (DBD) of STAT3, with anti-cancer properties.|
|Solubility||DMSO: ≥ 150 mg/mL|
|Storage||Store in a cool and dry place (or refer to the Certificate of Analysis).|
|Boiling Point||630.5±55.0 ℃ at 760 Torr|
Alantolactone is sesquiterpene lactone, significantly reduces feeding and survival of Tribolium confusum.
ISS610 is a Signal transducer and activator of transcription 3 (STAT3) inhibitor. Reported has shown that aberrant activation of oncogenic signal transducer and...
inS3-54A18 is a potent inhibitor of the DNA-binding domain (DBD) of STAT3, with anti-cancer properties.
Nifuroxazide is a cell-permeable and orally available nitrofuran-based antidiarrheal agent that effectively suppresses the activation of cellular STAT1/3/5 tran...
S31-201 is benezoic acid based small molecule, which inhibits the Stat3 transcription factor by blocking the phosphorylation and dimerization events necessary f...
SD 1008 is a JAK2/STAT3 signaling pathway inhibitor that inhibits activation of STAT3, JAK2 and Src. SD 1008 induces apoptosis in cell lines expressing constitu...
Golotimod is an orally bioactive synthetic peptide containing the amino acids D-glutamine and L-tryptophan connected by a gamma-glutamyl linkage with potential ...
STAT5-IN-1, a cell-permeable nonpeptidic nicotinoyl hydrazone compound, is a selective STAT5 inhibitor with an IC50 of 47 μM for STAT5β isoform with much less e...
AS 1517499 is a potent and selective STAT6 inhibitor (IC50 = 21 nM).
BP-1-102 is a potent and selective STAT3 inhibitor. BP-1-102 inhibits the expression of genes including c-Myc, Cyclin D1, Bcl-xL, Survivin, VEGF, and KrÃ¼ppel-l...
SH5-07 is a robust hydroxamic acid-based STAT3 inhibitor with an IC50 of 3.9±0.6 μM in in vitro assay, which induce antitumor cell effects in vitro and antitumo...
APTSTAT3-9R is a specific STAT3-binding peptide with addition of a cell-penetrating motif. STAT3 has been reported to promote the proliferation, survival, metas...
SH-4-54 is a potent STAT inhibitor with KD of 300 nM and 464 nM for STAT3 and STAT5, respectively.
Cryptotanshinone, a natural cell-permeable diterpene quinone isolated from Salvia miltiorrhiza, it inhibits acetylcholinesterase (IC50 = 4.09 μM) and reduces Aβ...
Corylifol A is extracted from the seeds of Psoralea corylifolia L and belongs to phenolic compounds. It inhibits IL-6-induced STAT3 promoter activity in Hep3B c...