INDY - CAS 1169755-45-6
Catalog number:
1169755-45-6
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C12H13NO2S
Molecular Weight:
235.3
COA:
Inquire
Targets:
Microtubule/Tubulin | Tau
Description:
INDY,under the IUPAC name 1-(3-ethyl-5-hydroxy-1,3-benzothiazol-2-ylidene)propan-2-one, is a DYRK1A/B inhibitor (DYRK1B: IC50= 0.23μM; DYRKA: IC50= 0.230.24μM). It Reverses aberrant tau-phosphorylation.
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Brife Description:
Reverses aberrant tau-phosphorylation
Synonyms:
1-(3-ethyl-5-hydroxy-1,3-benzothiazol-2-ylidene)propan-2-one; INDY; 1169755-45-6
Solubility:
Soluble to 100 mM in DMSO
Storage:
Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -44℃ for long term (months to years).
MSDS:
Inquire
Melting Point:
146.98ºC (Predicted).
InChIKey:
GCSZJMUFYOAHFY-UHFFFAOYSA-N
InChI:
1S/C12H13NO2S/c1-3-13-10-7-9(15)4-5-11(10)16-12(13)6-8(2)14/h4-7,15H,3H2,1-2H3
Canonical SMILES:
CCN1C2=C(C=CC(=C2)O)SC1=CC(=O)C
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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