|Description||Indisulam is a carbonic anhydrase inhibitor and a novel synthetic sulfonamide that targets the G1 phase of the cell cycle. The potential antitumor activity of Indisulam was discovered through optimization of the structure-activity relationships of a series of sulfonamide structures. Indisulam causes a blockade in the G1/S transition through inhibition of the activation of both cyclin-dependent kinase 2 and cyclin E. Preclinical studies with Indisulam showed activity in multiple tumor types, most prominently in colon and lung cancer.|
|B0084-085373||100 mg||$389||In stock|
|Brife Description||carbonic anhydrase inhbitor|
|Appearance||White to Pink Solid Powder|
|Synonyms||E7070; E 7070; E-7070; ER35744; ER 35744; ER-35744; D04522; N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonamide; 4-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonamide|
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