|Description||Indirubin-3'-monoxime, a chemical derivative of indirubin, is an inhibitor of GSK-3β with dual affinity for CDK1/5 receptor. It significantly inhibited the proliferation and induced apoptosis in all of the RCC cell lines. IC50: GSK-3β= 22nM; CDK1/5= 180/1|
|Appearance||Dark Red Solid|
|Synonyms||3-[3-(hydroxyamino)-1H-indol-2-yl]indol-2-one INDIRUBIN-3'-MONOXIME indirubin-3'-oxime 160807-49-8 indirubin-3-oxime Indirubin-3monoxime indirubin-3'-monooxime 3-[3-(Hydroxyamino)-1H-indol-2-yl]indol-2-one Indirubin-3′-monoxime CHEMBL126077 CHEBI:43|
|Solubility||DMSO: ≥ 37 mg/mL|
|Storage||Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -24℃ for long term (months to years).|
|Shelf Life||2 years|
|Boiling Point||532.2±50.0 °C | Condition: Press: 760 Torr|
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