Indirubin-3'-monoxime - CAS 160807-49-8
Catalog number:
160807-49-8
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C16H11N3O2
Molecular Weight:
277.28
COA:
Inquire
Targets:
GSK-3
Description:
Indirubin-3'-monoxime, a chemical derivative of indirubin, is an inhibitor of GSK-3β with dual affinity for CDK1/5 receptor. It significantly inhibited the proliferation and induced apoptosis in all of the RCC cell lines. IC50: GSK-3β= 22nM; CDK1/5= 180/1
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Appearance:
Dark Red Solid
Synonyms:
3-[3-(hydroxyamino)-1H-indol-2-yl]indol-2-one INDIRUBIN-3'-MONOXIME indirubin-3'-oxime 160807-49-8 indirubin-3-oxime Indirubin-3monoxime indirubin-3'-monooxime 3-[3-(Hydroxyamino)-1H-indol-2-yl]indol-2-one Indirubin-3′-monoxime CHEMBL126077 CHEBI:43
Solubility:
DMSO: ≥ 37 mg/mL
Storage:
Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -24℃ for long term (months to years).
MSDS:
Inquire
Shelf Life:
2 years
Quantity:
Grams-Kilos
Boiling Point:
532.2±50.0 °C | Condition: Press: 760 Torr
Density:
1.50±0.1 g/cm3
InChIKey:
LDEWQRSYYHTQRA-UHFFFAOYSA-N
InChI:
1S/C16H11N3O2/c20-16-13(9-5-1-3-7-11(9)18-16)15-14(19-21)10-6-2-4-8-12(10)17-15/h1-8,17,19,21H
Canonical SMILES:
C1=CC=C2C(=C1)C(=C(N2)C3=C4C=CC=CC4=NC3=O)NO
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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CAS 160807-49-8 Indirubin-3'-monoxime

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