|Description||Indinavir is a protease inhibitor used as a component of highly active antiretroviral therapy to treat HIV infection and AIDS. It inhibits the HIV-1 protease with an IC50 value of 0.41 nM and Ki value of 0.24 nM. However, indinavir demonstrates up to a 50-fold loss in potency against the HIV-1 protease drug-resistant mutations PRL24I, PRI50V, and PRG73S (Kis = 1.4, 27, and 0.55 nM).|
|Synonyms||Crixivan sulfate; MK-639 sulfate; L-735524 sulfate; MK639 sulfate; L735524 sulfate; MK 639 sulfate; L 735524 sulfate|
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Indinavir is a protease inhibitor used as a component of highly active antiretroviral therapy to treat HIV infection and AIDS. It inhibits the HIV-1 protease wi...
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Selective CCR5 antagonist
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HIV-1 integrase inhibitor 2
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A selective HIV protease inhibitor. Antiviral.