Indimilast - CAS 1038825-85-2
Catalog number:
1038825-85-2
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C37H40FN7O3S
Molecular Weight:
681.83
COA:
Inquire
Targets:
Phosphodiesterase (PDE)
Description:
Indimilast is a phosphodiesterase IV inhibitor. It modulates lung inflammation and cause bronchodilation by increasing intracellular cyclic adenosine 3', 5'-monophosphate in airway smooth muscle and inflammatory cells. It is potential useful in chronic obstructive pulmonary disease(COPD).
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Purity:
>98 %
Appearance:
Solid powder
Synonyms:
N-[4-[1-[3-[4-[[(3S,5R)-3,5-dimethylpiperazin-1-yl]methyl]phenyl]phenyl]-6-fluoro-2,4-dioxopyrido[2,3-d]pyrimidin-3-yl]cyclohexyl]-2-methyl-1,3-thiazole-4-carboxamide;N-{cis-4-[1-(4'-{[(3R,5S)-3,5-dimethylpiperazin-1-yl]methyl}[1,1'-biphenyl]-3-yl)-6-fluoro-2,4-dioxo-1,4-dihydropyrido[2,3-d]pyrimidin-3(2H)-yl]cyclohexyl}-2-methyl-1,3-thiazole-4-carboxamide
Solubility:
10 mM in DMSO
Storage:
-20°C Freezer
MSDS:
Inquire
Application:
Indimilast is potential useful in chronic obstructive pulmonary disease(COPD).
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Milligrams-Grams
Density:
1.38±0.1 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr
InChIKey:
MKQDRXQEQLCSON-KUKIJGICSA-N
InChI:
InChI=1S/C37H40FN7O3S/c1-22-18-43(19-23(2)40-22)20-25-7-9-26(10-8-25)27-5-4-6-31(15-27)44-34-32(16-28(38)17-39-34)36(47)45(37(44)48)30-13-11-29(12-14-30)42-35(46)33-21-49-24(3)41-33/h4-10,15-17,21-23,29-30,40H,11-14,18-20H2,1-3H3,(H,42,46)/t22-,23+,29?,30
Canonical SMILES:
CC1CN(CC(N1)C)CC2=CC=C(C=C2)C3=CC(=CC=C3)N4C5=NC=C(C=C5C(=O)N(C4=O)C6CCC(CC6)NC(=O)C7=CSC(=N7)C)F
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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