|Description||Indibulin, also called D 24851, estabilizes tubulin polymerization (IC50 = 0.3 μM) and induces tumor cell cycle arrest and apoptosis. In vitro: blocking cell cycle progression at metaphase; In vivo: induce complete tumor remission in the Yoshida AH13 rat sarcoma model|
|Brife Description||Estabilizes tubulin polymerization; Induces tumor cell cycle arrest and apoptosis|
|Synonyms||2-[1-[(4-chlorophenyl)methyl]indol-3-yl]-2-oxo-N-pyridin-4-ylacetamide; D 24851; D-24851; indibulin; N-(pyridin-4-yl)-(1-(4-chlorobenzyl)indol-3-yl)glycoxylamide; N-(pyridin-4-yl)-(1-(4-chlorobenzyl)indol-3-yl)glyoxylamide|
|Solubility||Soluble to 25 mM in DMSO|
|Storage||Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -60℃ for long term (months to years).|
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