Incyclinide - CAS 15866-90-7
Catalog number:
15866-90-7
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
COA:
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Description:
incyclinide, also known as CMT-3 and COL-3, is a MMP inhibitor and achemically-modified tetracycline with potential antineoplastic activity. Incyclinide inhibits matrix metalloproteinases (MMPs), thereby inducing extracellular matrix degradation, and inhibiting angiogenesis, tumor growth and invasion, and metastasis. This agent also causes mitochondrial depolarization in tumor cells and induces both cellular apoptosis and tissue necrosis.
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Appearance:
white solid powder
Synonyms:
Metastat; 4-dedimethylamino sancycline; CMT-3; COL 3.
MSDS:
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Current Developer:
CollaGenex Pharmaceuticals, Inc.
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CAS 15866-90-7 Incyclinide

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