INCB024360-analog - CAS 914471-09-3
Catalog number: 914471-09-3
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C9H7ClFN5O2
Molecular Weight:
271.64
COA:
Inquire
Targets:
IDO
Description:
Potent competitive inhibitor of IDO1 with in vivo pharmacodynamic activity and efficacy in a mouse melanoma model; This INCB024360-analog decreased kynurenine levels by >50% in plasma and inhibited B16-GM-CSF tumor growth in a dose dependent fashion.
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Brife Description:
An orally available hydroxyamidine and inhibitor of IDO1, with potential immunomodulating and antineoplastic activities.
Purity:
> 98%
Appearance:
Off-white solid
Synonyms:
INCB-24360; INCB024360; INCB 024360; INCB-024360; indoleamine-2,3-dioxygenase inhibitor INCB024360.
Solubility:
DMSO 58 mg/mL
Storage:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
MSDS:
Inquire
Quality Standard:
In-house
Shelf Life:
>2 years if stored properly
Quantity:
Grams-Kilos
Boiling Point:
~318.6 °C at 760 mmHg (Predicted)
Melting Point:
154.74 °C (Predicted)
InChIKey:
HGXSLPIXNPASGZ-UHFFFAOYSA-N
InChI:
1S/C9H7ClFN5O2/c10-5-3-4(1-2-6(5)11)13-9(14-17)7-8(12)16-18-15-7/h1-3,17H,(H2,12,16)(H,13,14)
Canonical SMILES:
O/N=C(C1=NON=C1N)/NC2=CC=C(F)C(Cl)=C2
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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